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Hepagurd
Beximco Pharmaceuticals Ltd.
Generic: L-Ornithine + L-Aspartate
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Hepagurd. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Hepagurd during pregnancy is not available. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Hepagurd during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR
It is not known whether Hepagurd alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CONSULT YOUR DOCTOR
There is limited information available on the use of Hepagurd in patients with kidney disease. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Hepagurd in patients with liver disease. Please consult your doctor.
Medicine Overview of Hepagurd 3gm/sachet Sachet
Introduction
Hepagurd is used in the treatment of liver disease. It protects the liver from harmful chemical substances and improves the functioning of the liver. Hepagurd is to be taken in dose and duration as prescribed by your doctor. You can take it with or without food. You must take the medicine regularly at a fixed time each day to get the maximum benefit from it. Taking more than recommended doses of this medicine may have harmful effects on your health. The course of the treatment must be completed for better efficacy. This medicine is generally well tolerated with little or...
... Show moreUses of Hepagurd
- Liver disease
Side effects of Hepagurd
Common
- No common side effects seen
How to use Hepagurd
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Hepagurd may be taken with or without food, but it is better to take it at a fixed time.
How Hepagurd works
Hepagurd is a combination of two amino acids which works by protecting the liver from harmful chemical substances (free radicals), thus preventing liver damage.
Brief Description
Indication
Acute Hepatitis (Viral, non-viral, drug induced), Chronic Hepatitis (with or without hyperammonaemia), Cirrhosis of Liver, Fatty Liver with hyperammonaemia, Hepatic Encephalopathy,
As an adjuvant therapy with all hepatotoxic drugs
Administration
Infusion concentrate
1) Infusion concentrate can be added to any of the conventional intravenous fluids (0.9% sodium chloride, 5% dextrose and Ringer's lactate etc.)
2) The normal dilution rate is 1 ampoule per 100ml of I.V. fluid. However, the dose should not exceed 6 ampoules per 500 ml. infusion. The solution mixtures were stable up to 24 hours.
3) Infusion Rate: 5 g/h at maximum.
Oral
Should be taken during or after meal.
Adult Dose
Injection (Infusion Concentrate)
The recommended dose is up to 20 g (4 ampoules daily).
In case of loss of consciousness (pre-coma) and clouding of consciousness (coma) up to 8 ampoule within 24 hours,depending on the severity of the condition.
Oral
1-2 sachets is dissolved in a large amount of fluid (e.g. in a glass of water or juice) and is taken orally 3 times a day.
Contraindication
Patients with severe renal insufficiency.
Mode of Action
Endogenous Amino Acids, L-Ornithine and L-Aspartate. After administration, it quickly breaks down into L-Ornithine and L-Aspartate. L-Ornithine being a substrate of urea cycle, converts toxic ammonia into non-toxic urea which is eliminated via kidneys, helping the diseased liver to carry out its normal function smoothly (detoxification). The process lowers the elevated level of ammonia in blood (hyperammonaemia) which is a common problem in most of the liver diseases.
L-Aspartate is an essential component of citric acid cycle which liberates energy (ATP), and thus helps in regeneration of damaged liver cells.
Precaution
Caution needed for pregnant and breastfeeding women.
Side Effect
Increased wt; depressed mood, sleep disorder, nervousness, loss of libido, altered mood; headache, migraine; nausea, abdominal pain or distension, flatulence, vomiting; diarrhea, acne; alopecia; back pain; breast discomfort, ovarian cyst, hot flush, uterine/vaginal bleeding including spotting; asthenic conditions, irritability etc.
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