Introduction
Betaclox is a penicillin-type of antibiotic used to treat various bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract, and skin and soft tissue. It mainly fights and stops the growth of the gram-positive type of bacteria.
Betaclox should be taken on an empty stomach. For best results, it should be used regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication.
Before taking this medicine, inform your doctor if you are allergic to penicillin or penicillin-type of medicine. Rash, vomiting, allergic reactions, nausea and diarrhea may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor's supervision.
Side effects of Klox-D Capsule
Common
- Rash
- Vomiting
- Allergic reaction
- Nausea
- Diarrhea
How to use Klox-D Capsule
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Betaclox is to be taken empty stomach.
How Klox-D Capsule works
Betaclox is an antibiotic. It kills bacteria by preventing them from forming their own protective covering (cell wall) which is needed for them to survive.
Indication
Pneumonia, Endocarditis, Impetigo, Cellulitis, Septic Arthritis, Surgical Prophylaxis, Otitis externa, Staphylococcal skin infections, Folliculitis, Boils, Carbuncles, Mastitis, Osteomyelitis, Throat infections, Streptococcus Septicaemia
Administration
Should be taken on an empty stomach. Take on an empty stomach at least 1 hr before or 2 hr after meals.
Adult Dose
Oral
Staphylococcus aureus infections
125-500 mg PO q6hr
Child Dose
Child: PO 12–25 mg/kg/day q6h
For bone and joint infections, up to 100 mg/kg/day
Contraindication
Hypersensitivity to penicillins.
Mode of Action
Dicloxacillin has antimicrobial action similar to benzylpenicillin and includes penicillinase-producing and non-penicillinase-producing staphylococci. It is active against streptococci eg, S. pneumoniae and S. pyogenes is < that of benzylpenicillin, but sufficient to be useful when these organisms are present with penicillin-resistant staphylococci. It is ineffective against E. faecalis.
Precaution
Very high doses in poor renal function (risk of neurotoxicity) or heart failure. Skin sensitization may occur on direct contact. Monitor serum K concentration, renal and hematological status. Spirochete infections particularly syphilis; suprainfection with penicillin-resistant organisms with prolonged use; avoid intrathecal route; elderly; porphyria.
Lactation: excreted in breast milk, use caution
Side Effect
1-10%
Abdominal pain,Diarrhea,Nausea
<1%
Anemia,Elevated LFTs,Fever,Hypersensitivity,Nephritis,Pseudomembranous colitis,Seizures with extremely high doses &/or renal failure,Rash (maculopapular to exfoliative),Vomiting,Vaginitis
Potentially Fatal: Anaphylaxis.
Pregnancy Category Note
Pregnancy Category: B
Lactation: excreted in breast milk, use caution
Interaction
Probenecid prolongs serum levels of dicloxacillin. Bacteriostatic drugs (e.g. chloramphenicol, tetracyclines) may antagonise the bactericidal effect of dicloxacillin. May reduce anticoagulant response to dicumarol and warfarin. May increase risk of methotrexate toxicity. May diminish the effect of live vaccines (e.g. typhoid vaccine).