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Sanofi Bangladesh Ltd.
Generic: Chlorpromazine Hydrochloride
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descriptionSafety Advices
It is unsafe to consume alcohol with Largactil.
Largactil may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developi... View More
Largactil is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. If t... View More
Largactil may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Largactil is safe to use in patients with kidney disease. No dose adjustment of Largactil is recommended. However, inform your doctor if you have any un... View More
There is limited information available on the use of Largactil in patients with liver disease. Please consult your doctor.
descriptionMedical Overview


Largactil is a medicine used to treat various disorders such as schizophrenia and other psychoses like paranoia (delusions and feeling extremely worried... View More

Uses of Largactil

  • Schizophrenia

Side effects of Largactil

  • Sleepiness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Dryness in mouth
  • Abnormality of voluntary movements
  • Weight gain
  • Increased prolactin level in blood
  • Urinary retention
  • Constipation
  • Muscle stiffness

How to use Largactil

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Largactil may be taken wit... View More

How Largactil works

Largactil is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

quick tipsQuick Tips
  • Take it at night to avoid feeling sleepy during the day.
  • Do not drive or do anything requiring concentration until you know how CPZ 50 Tablet affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Do not drink alcohol while taking CPZ 50 Tablet as it can cause serious breathing problems.
  • Inform your doctor if you notice involuntary muscle movements.
  • Monitor your weight during the treatment as CPZ 50 Tablet can cause weight gain.
  • Do not stop taking the medication suddenly without talking to your doctor.
descriptionBrief Description


Schizophrenia, Bipolar disorder, Anxiety, Psychoses, Delirium, Porphyria, Hiccups, Nausea, Vomiting


May be taken with or without food. May be taken w/ meals to reduce GI discomfort. Direct IV injection is only for control of nausea and vomiting duri... View More

Adult Dose

Schizophrenia, Psychotic Disorders PO: 30-75 mg/day divided q6-12hr initially; maintenance: usually 200 mg/day (up to 800 mg/day in some patients; some... View More

Child Dose

Behavioral Disorders, Hyperactivity >6 months: 50-100 mg/day PO/IM; 200 mg/day or more may be necessary for older hospitalized patients; for outpatient... View More


Do not use in patients with known hypersensitivity to phenothiazines. Do not use in comatose states or in the presence of large amounts of central ne... View More

Mode of Action

Chlorpromazine is a neuroleptic that acts by blocking the postsynaptic dopamine receptor in the mesolimbic dopaminergic system and inhibits the release ... View More


Some patients exposed chronically to antipsychotics will develop tardive dyskinesia, Chlorpromazine should be administered cautiously to persons with... View More

Side Effect

Extrapyramidal symptoms. Tardive dyskinesia (on long-term therapy). Involuntary movements of extremities may also occur. Dry mouth, constipation, urinar... View More

Pregnancy Category Note

Pregnancy category: C; neonates exposed to antipsychotic drugs during 3rd trimester of pregnancy are at risk for EPS or withdrawal symptoms after delive... View More


Potentiation of anticholinergic effects of antiparkinson agents and TCAs may lead to an anticholinergic crisis. Additive orthostatic hypotensive effect ... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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