Lithium SR is a prescription medicine used in the treatment of bipolar disorder and mania in adults. It is sometimes used to treat other behavioral diso... View More
Uses of Lithium SR
Side effects of Lithium SR
How to use Lithium SR
Use it as advised by your doctor or check the label for directions before use. Lithium SR is to be taken with food.
How Lithium SR works
Lithium SR works by suppressing the abnormal and excessive activity of the nerve cells in the brain.
Bipolar disorder, Mania, Recurrent unipolar depression
Should be taken with food.
Oral Mania; Bipolar disorder; Recurrent unipolar depression Adult: Treatment and prevention: Initially, 400-1,200 mg daily in 1-2 divided doses. S... View More
Renal impairment: CrCl (ml/min) Dosage Recommendation 10-50 50-75% of normal dose. <10 25-50% of normal dose.
Renal insufficiency, cardiovascular insufficiency, Addison\'s disease and untreated hypothyroidism are all contraindications to lithium therapy.
Mode of Action
Inhibits postsynaptic D2 receptor supersensitivity. Alters cation transport in nerve and muscle cells and influences reuptake of serotonin or norepineph... View More
Decreased tolerance to lithium has been reported to ensue from protracted sweating or diarrhoea and, if such occur, supplemental fluid and salt should b... View More
>10% Leukocytosis (most patients),Polyuria/polydypsia (30-50%),Dry mouth (20-50%),Hand tremor (45% initially, 10% after 1 year of treatment),Confusion ... View More
Reduced serum levels with carbonic anhydrase inhibitors, chlorpromazine, sodium-containing preparations, theophylline, urea. Enhanced hypothyroid effect... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More