Popular Pharmaceuticals Ltd.
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Caution is advised when consuming alcohol with Locol 10. Please consult your doctor.
Locol 10 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful eff... View More
Locol 10 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Locol 10 does not usually affect your ability to drive.
Locol 10 is safe to use in patients with kidney disease. No dose adjustment of Locol 10 is recommended. However, inform your doctor if you have any unde... View More
Locol 10 should be used with caution in patients with liver disease. Dose adjustment of Locol 10 may be needed. Please consult your doctor. Use of Locol... View More
Locol 10 belongs to a group of medicines called statins. It is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fatty... View More
Uses of Locol 10
- High cholesterol
- Prevention of heart attack
Side effects of Locol 10
- Muscle pain
How to use Locol 10
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Locol 10 may be taken with... View More
How Locol 10 works
Locol 10 is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. I... View More
What if you forget to take Locol 10?
If you miss a dose of Locol 10, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More
- In general, Locol 10 is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
- Inform your doctor if you experience fatigue, muscle weakness or muscle pain.
- Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver proble... View More
- Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your... View More
- Do not take Locol 10 if you are pregnant, planning a pregnancy or breastfeeding.
Oral Mixed dyslipidaemia, Heterozygous familial hypercholesterolaemia, Nonfamilial hypercholesterolaemia Adult: Initially, 10 or 20 mg once daily, may... View More
May increase risk of myopathy and rhabdomyolysis w/ CYP3A4 potent inhibitor (e.g. HIV or HCV protease inhibitors, itraconazole, clarithromycin), fenofib... View More
Patients who consume substantial quantities of alcohol. History of liver disease. Patients with risk factors for myopathy or rhabdomyolysis. Hypothyroid... View More
Atorvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyses the conversion of HMG-CoA to mevalonate. This results in the induction ... View More
Oral Mixed dyslipidaemia, Heterozygous familial hypercholesterolaemia, Nonfamilial hypercholesterolaemia Child: Heterozygous familial hypercholesterol... View More
Mode of Action
Atorvastatin can be administered as a single dose at any time of the day, with or without food. Avoid excessive consumption (>1 L/day) of grapefruit jui... View More
Primary hypercholesterolemia (heterozygous familial and nonfamilial), Mixed Dyslipidemia, Homozygous familial hypercholesterolemia, Hypertriglyceridemi... View More
Renal Insufficiency: Renal disease does not affect the plasma concentrations or LDL-C reduction of atorvastatin; thus, dosage adjustment in patients wit... View More
Pregnancy Category Note
>10% Diarrhea (5-14%),Nasopharyngitis (4-13%),Arthralgia (4-12%) 1-10% Insomnia (1-5%),Urinary tract infection (4-8%),Nausea (4-7%),Dyspepsia (3-6%... View More
Hypersensitivity, active liver disease or unexplained persistent elevations of serum transaminase, porphyria, pregnancy, lactation.
Alternative brand for Locol 10
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More