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Neoclomide50mg

Tablet
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Healthcare Pharmaceuticals Ltd.
Generic: Cyclophosphamide
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Neoclomide.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Neoclomide is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it i... View More
BreastfeedingBreastfeeding
UNSAFE
Neoclomide is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
UNSAFE
Neoclomide may cause side effects which could affect your ability to drive. Neoclomide may cause undesirable effects (e.g., dizziness, blurred vision, v... View More
KidneyKidney
CAUTION
Neoclomide should be used with caution in patients with severe kidney disease. Dose adjustment of Neoclomide may be needed. Please consult your doctor.
LiverLiver
CAUTION
Neoclomide should be used with caution in patients with liver disease. Dose adjustment of Neoclomide may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Neoclomide is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after... View More

Uses of Neoclomide

  • Cancer
  • Nephrotic syndrome

Side effects of Neoclomide

Common
  • Vomiting
  • Nausea
  • Hair loss
  • Fever
  • Blood in urine
  • Diarrhea
  • Decreased white blood cell count (neutrophils)

How to use Neoclomide

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Neoclomide is to be taken ... View More

How Neoclomide works

Neoclomide is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, there... View More

quick tipsQuick Tips
  • Neoclomide helps in the treatment of cancer.
  • Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
  • Take it with food if you experience irritation of the stomach, preferably in the morning.
  • Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
  • You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
  • Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
  • Do not take Neoclomide if you are pregnant or breastfeeding.
  • Use effective contraception method to prevent pregnancy while taking this medicine.
descriptionBrief Description

Indication

Bone marrow transplantation, malignancies, lymphomas, brain cancer, leukemia, systemic lupus erythematosus, minimal change disease, severe rheumatoid ar... View More

Administration

Should be taken on an empty stomach. Preferably taken on an empty stomach, but may be taken w/ meals to minimise GI irritation. Ensure adequate fluid in... View More

Adult Dose

Malignant Diseases IV (intermittent therapy): 40-50 mg/kg (400-1800 mg/m²) divided over 2-5 days; may be repeated at intervals of 2-4 weeks IV (cont... View More

Child Dose

Malignant Diseases IV (intermittent therapy): 40-50 mg/kg (400-1800 mg/m²) divided over 2-5 days; may be repeated at intervals of 2-4 weeks IV (cont... View More

Contraindication

Bladder haemorrhage. Patients with bone-marrow aplasia, acute infection, drug- or radiation-induced urothelial toxicity. Porphyria. Pregnancy and lactat... View More

Mode of Action

Cyclophosphamide is a prodrug which is converted in the body to the active metabolites. It acts at any stage of the cell cycle but its main action is bl... View More

Precaution

Blood disorders. Elderly or debilitated patients. Diabetic patients. Renal or hepatic impairment or who have gone adrenaloctomy. Previous treatment with... View More

Side Effect

Alopecia, skin and nails hyperpigmentation, nausea and vomiting, mucositis, inappropriate antidiuretic hormone secretion, carbohydrate metabolism distur... View More

Pregnancy Category Note

Pregnancy Based on mechanism of action and published reports of effects in pregnant patients or animals, drug can cause fetal harm when administered to... View More

Interaction

Increased risk of cardiotoxicity w/ doxorubicin or other cardiotoxic drugs. May increase incidence of mucositis w/ protease inhibitors. May increase hae... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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