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Square Pharmaceuticals PLC.
Generic: Sodium polystyrene sulfonate
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descriptionMedical Overview




Oral Preparation For each gram of powdered resin add 3-4 mL of water or syrup Do not heat solution to improve dissolution; heat impairs resin exchange... View More

Adult Dose

Oral Hyperkalaemia Adult: As suspension in water or syrup or as sweetened paste: 15 g up to 4 times daily. Not to be taken with fruit juices that have... View More

Child Dose

Oral Hyperkalaemia Child: Acute hyperkalaemia: 1 g/kg daily in divided doses. Maintenance: 500 mg/kg daily. Rectal Hyperkalaemia Child: and neo... View More


Hypersensitivity to polystyrene sulfonate resins. Oral admin to neonates; neonates with reduced gut motility; obstructive bowel disease. Hypokalaemia.

Mode of Action

Sodium polysytrene sulfonate exchanges sodium ions for potassium ions and other cations in the GI tract before the resin is excreted in the faeces.


Renal failure and conditions requiring a restricted sodium intake e.g. heart failure and severe hypertension. Rectal admin to neonates and children. Mon... View More

Side Effect

1-10% GI disturbance Constipation Hypokalemia Hypocalcemia Hypomagnesemia Sodium retention Nausea Vomiting Frequency Not Defined GI concreti... View More


Reduces absorption of thyroxine and lithium salts. Enhances adverse effects of cardiac glycosides. Potassium-lowering effect may be reduced when used wi... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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