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Apilast
Apilast
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সারা বাংলাদেশ থেকে অর্ডার করা যাবে।

Apilast10mg

Tablet
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Labaid Pharmaceuticals Ltd.
Generic: Apremilast
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22.50
MRP
25.00
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descriptionSafety Advices
AlcoholAlcohol
CAUTION
Caution is advised when consuming alcohol with Apilast. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Apilast may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of Apilast during breastfeeding is not available. Please consult your doctor.
DrivingDriving
SAFE
Apilast does not usually affect your ability to drive.
KidneyKidney
CAUTION
Apilast should be used with caution in patients with severe kidney disease. Dose adjustment of Apilast may be needed. Please consult your doctor.
LiverLiver
SAFE IF PRESCRIBED
Apilast is safe to use in patients with liver disease. No dose adjustment of Apilast is recommended.
descriptionMedical Overview

Introduction

Apilast is used in the treatment of moderate to severe plaque psoriasis which is a type of skin condition. This medicine is used when other conventional... View More

Uses of Apilast

  • Plaque psoriasis

Side effects of Apilast

Common
  • Diarrhea
  • Nausea
  • Vomiting

How to use Apilast

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apilast may be taken with ... View More

How Apilast works

Apilast is a phosphodiesterase 4 (PDE4) inhibitors. It works by blocking the action of certain chemical messengers that are responsible for inflammation... View More

quick tipsQuick Tips
  • Apilast is a well-tolerated medicine. Mild stomach upset may occur early during the treatment.
  • Monitor your weight regularly as Apilast may cause weight loss.
  • Your doctor will gradually increase the dose from day 1 to day 6 of treatment, after which it may be kept constant.
  • Tell your doctor immediately if you experience new or worsened depression, suicidal thoughts, other mood changes or unexplained weight loss.
descriptionBrief Description

Indication

Active psoriatic arthritis, moderate to severe plaque psoriasis

Administration

To reduce risk of GI symptoms associated with initial therapy, titrate to recommended dose (30 mg PO BID) according to the dosage schedules listed above... View More

Adult Dose

Active psoriatic arthritis, moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate. To reduce risk of gastrointes... View More

Renal Dose

Severe renal impairment (CrCl <30 mL/min): Reduce dose to 30 mg PO qDay Mild-to-moderate renal impairment: No dosage adjustment required

Contraindication

Known hypersensitivity to apremilast.

Mode of Action

Apremilast is an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4) specific for cyclic adenosine monophosphate (cAMP). PDE4 inhibition results... View More

Precaution

Apremilast is associated with an increase in adverse reactions of depression. Before using, evaluate patient for history of depression and/or suicidal t... View More

Side Effect

1-10% Diarrhea (7.7-9.3%),Nausea (7.4-8.9%),Headache (4.8-5.9%),Upper respiratory tract infection (0.6-3.9%),Vomiting (0.8-3.2%),Nasopharyngitis (0.2-2... View More

Pregnancy Category Note

Pregnancy Available pharmacovigilance data use in pregnant women have not established a drug-associated risk of major birth defects, miscarriage or adv... View More

Interaction

Coadministration with strong CYP inducers (eg, rifampin, carbamazepine, phenobarbital phenytoin) may occur and result in a loss of efficacy of apremilas... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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