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Pendoril 4 may cause excessive drowsiness with alcohol.
Pendoril 4 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it i... View More
Pendoril 4 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Pendoril 4 may cause side effects which could affect your ability to drive. Pendoril 4 usually does not affect alertness but dizziness or weakness due t... View More
Pendoril 4 should be used with caution in patients with kidney disease. Dose adjustment of Pendoril 4 may be needed. Please consult your doctor. Caution... View More
Pendoril 4 should be used with caution in patients with liver disease. Dose adjustment of Pendoril 4 may be needed. Please consult your doctor. Inform y... View More
Pendoril 4 belongs to a group of medicines known as angiotensin converting enzyme (ACE) inhibitor. It is widely used to treat high blood pressure and he... View More
Uses of Pendoril 4
- Hypertension (high blood pressure)
- Prevention of heart attack and stroke
- Heart failure
Side effects of Pendoril 4
- Decreased blood pressure
- Increased potassium level in blood
How to use Pendoril 4
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pendoril 4 is to be taken ... View More
How Pendoril 4 works
Pendoril 4 is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows m... View More
What if you forget to take Pendoril 4?
If you miss a dose of Pendoril 4, skip it and continue with your normal schedule. Do not double the dose.
- Pendoril 4 can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedti... View More
- Let your doctor know about any cough, or throat irritation that does not go away.
- It may increase the level of potassium in blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Hypertension, IHD, Heart failure
Should be taken on an empty stomach. Take before meals.
Oral Adult Hypertension 4-8 mg PO qDay or divided q12hr Maximum: 16 mg/day PO divided q12hr Stable Coronary Artery Disease (CAD) 4 mg PO qDay ... View More
Renal impairment: CrCl (ml/min) Dosage Recommendation <15 2 mg on dialysis days. 15-30 2 mg on alternate days. 30-60 2 mg
History of angioedema related to previous ACE inhibitor treatment. Pregnancy (2nd/3rd trimesters).
Mode of Action
Perindopril is an ACE inhibitor, which acts by inhibiting the conversion of angiotensin I to angiotensin II, reducing the activity of the sympathetic ne... View More
History of airway surgery. Withdraw if there is significant increase in LFTs. Risk factors for hyperkalaemia; monitor potassium closely. Patients depend... View More
>10% Headache (23%),Cough (12%) 1-10% Dizziness (8%),Back pain (6%),Lower extremity pain (5%),Abnormal ECG (2%),Palpitation (1%),Depression (2%),So... View More
May enhance hypotensive effect w/ diuretics. Additive hyperkalaemic effect w/ K supplements, K-sparing diuretics, and other drugs (e.g. ciclosporin, hep... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More