Introduction
Powergra 50 is a prescription medicine used to treat erectile dysfunction (impotence) in men. It works by increasing blood flow to the penis. This helps... View More
Uses of Powergra 50
Side effects of Powergra 50
How to use Powergra 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Powergra 50 may be taken w... View More
How Powergra 50 works
Powergra 50 is a phosphodiesterase-5 (PDE-5) inhibitor. It works by relaxing the blood vessels in your penis, thereby increasing blood flow into the pen... View More
What if you forget to take Powergra 50?
If you miss a dose of Powergra 50, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
Indication
Erectile dysfunction, Pulmonary arterial hypertension
Administration
May be taken with or without food.
Adult Dose
Oral Erectile dysfunction Adult: 50 mg about 1 hr before sexual intercourse. May adjust dose depending on penile response. Max: 100 mg/dose and not ... View More
Renal Dose
Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Initially, 25 mg.
Contraindication
Hypersensitivity. Patients concurrently or intermittently using organic nitrates in any form.
Mode of Action
Sildenafil inhibits phosphodiesterase type-5 (PDE5) which is responsible for cGMP degradation in the corpus cavernosum. Inhibition of PDE5 increases cGM... View More
Precaution
Caution when used in patients with anatomical deformation of penis or conditions that may predispose them to priapism (e.g. sickle cell anaemia, myeloma... View More
Side Effect
>10% Headache (7-16%) 1-10% Flushing (4-10%),Epistaxis (8%),Dyspepsia (4-8%),Insomnia (6%),Erythema (5%),Diarrhea (4%),Dizziness (2%),Skin rash (2%... View More
Interaction
Inhibitors of CYP3A4 such as cimetidine and erythromycin are likely to reduce sildenafil clearance. CYP3A4 inducers such as rifampicin may decrease the ... View More
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More