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Apex Pharma Ltd.
Generic: Ramipril
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descriptionSafety Advices
Pril may cause excessive drowsiness with alcohol.
Pril is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some... View More
Pril is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pril may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Pril should be used with caution in patients with kidney disease. Dose adjustment of Pril may be needed. Please consult your doctor. Regular monitoring ... View More
Pril should be used with caution in patients with liver disease. Dose adjustment of Pril may be needed. Please consult your doctor. Inform your doctor i... View More
descriptionMedical Overview


Pril belongs to a group of medicines known as angiotensin converting enzyme (ACE) inhibitors. It is widely used to treat high blood pressure and heart f... View More

Uses of Pril

  • Hypertension (high blood pressure)
  • Prevention of heart attack and stroke
  • Heart failure

Side effects of Pril

  • Decreased blood pressure
  • Dizziness
  • Fatigue
  • Vomiting
  • Dry cough

How to use Pril

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pril may be taken with or ... View More

How Pril works

Pril is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more sm... View More

What if you forget to take Pril?

If you miss a dose of Pril, skip it and continue with your normal schedule. Do not double the dose.

quick tipsQuick Tips
  • Pril can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime to ... View More
  • Let your doctor know about any cough, or throat irritation that does not go away.
  • It may increase the level of potassium in blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
descriptionBrief Description


Congestive heart failure, MI, HTN, CV events, Stroke


May be taken with or without food.

Adult Dose

Oral Hypertension, Diabetic Nephropathy Adult: Hypertension Initial (not on diuretic): 2.5 mg once daily at bedtime. Initial (with diuretic): 1.25... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation 10-30 Initially, 1.25 mg/day. Max: 5 mg/day. 30-60 Not necessary to adjust the initial dose. Ma... View More


Hypersensitivity, bilateral renal artery stenosis, or a single kidney with unilateral renal artery stenosis. Aortic stenosis or outflow tract obstructio... View More

Mode of Action

Ramipril, a prodrug of ramiprilat, competitively inhibits ACE from converting angiotensin I to angiotensin II (a potent vasoconstrictor) resulting in in... View More


Renal impairment, hypovolaemia, hyperkalaemia, valvular stenosis; before, during or immediately after anaesthesia. Severe resistant hypertension, elderl... View More

Side Effect

>10% Cough (7-8%),Hypotension (2-11%) 1-10% Headache (1-5%),Angina pectoris (3%),Dizziness (2-4%),Nausea (2%),Vomiting (2%),Postural hypotension (2... View More


May enhance hypotensive effect w/ diuretics and other antihypertensives. May increase risk of renal function deterioration w/ NSAIDs. May increase serum... View More

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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