Purinol300mg
Tablet
Drug International Ltd.
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| Alcohol | CAUTION Caution is advised when consuming alcohol with Purinol. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Purinol may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing... View More |
| Breastfeeding | SAFE IF PRESCRIBED Purinol is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not ha... View More |
| Driving | UNSAFE Purinol may cause side effects which could affect your ability to drive.
Occasionally drowsiness, dizziness or vertigo, ataxia and visual disturbances, ... View More |
| Kidney | CAUTION Purinol should be used with caution in patients with kidney disease. Dose adjustment of Purinol may be needed. Please consult your doctor. |
| Liver | CAUTION Purinol should be used with caution in patients with liver disease. Dose adjustment of Purinol may be needed. Please consult your doctor. |
Introduction
Purinol is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals which can ap... View More
Uses of Purinol
- Gout
Side effects of Purinol
- Skin rash
- Diarrhea
- Nausea
How to use Purinol
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Purinol is to be taken wit... View More
How Purinol works
Purinol is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.
What if you forget to take Purinol?
If you miss a dose of Purinol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More
- Your doctor has prescribed Purinol to reduce episodes of gout attack.
- Take Purinol with food to avoid stomach upset.
- Take plenty of fluids (2-3 litres) daily while on Purinol.
- Notify your doctor if you develop a rash. This could be a sign of allergy and should go away on discontinuing Purinol.
- When you first start taking this medicine, you might have more gout attacks. Do not stop Purinol on having an acute attack of gout as that could make an... View More
- Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin... View More
- Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
Indication
Adult: PO Gout; Hyperuricaemia Mild: 100 mg/day PO initially; increased weekly to 200-300 mg/day Moderate to severe: 100 mg/day PO initially; incre... View More
Administration
May inhibit the metabolism of mercaptopurine and azathioprine; reduce dose of mercaptopurine and azathioprine when given w/ allopurinol. May increase ef... View More
Adult Dose
Ensure adequate fluid intake. Prophylactically with an anti-inflammatory or colchicine for at least 1 mth. Withdraw immediately when sensitivity (skin r... View More
Renal Dose
Allopurinol is an inhibitor of the enzyme xanthine oxidase which converts hypoxanthine to xanthine then uric acid. The reduced production of uric acid r... View More
Mode of Action
Administration Should be taken with food. Take immediately after meals.
Precaution
Hyperuricaemia, Uric acid nephropathy, Cancer therapy-induced hyperuricaemia, Gout, Recurrent renal stones
Side Effect
Renal impairment: Haemodialysis: Administer dose after session or administer 50% supplemental dose. CrCl (ml/min) 10-20 200 mg daily. <3 100 mg da... View More
Pregnancy Category Note
1-10% Rash (1.5%),Nausea (1.3%),Renal failure (1.2%),Vomiting (1.2%) Frequency Not Defined Amblyopia,Arthralgias,Blood dyscrasias,Bronchospasm,Card... View More
Interaction
Hypersensitivity; acute attack of gout.
Alternative brand for Purinol
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More