Purinol is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals which can ap... View More
Uses of Purinol
Side effects of Purinol
How to use Purinol
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Purinol is to be taken wit... View More
How Purinol works
Purinol is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.
What if you forget to take Purinol?
If you miss a dose of Purinol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More
Adult: PO Gout; Hyperuricaemia Mild: 100 mg/day PO initially; increased weekly to 200-300 mg/day Moderate to severe: 100 mg/day PO initially; incre... View More
May inhibit the metabolism of mercaptopurine and azathioprine; reduce dose of mercaptopurine and azathioprine when given w/ allopurinol. May increase ef... View More
Ensure adequate fluid intake. Prophylactically with an anti-inflammatory or colchicine for at least 1 mth. Withdraw immediately when sensitivity (skin r... View More
Allopurinol is an inhibitor of the enzyme xanthine oxidase which converts hypoxanthine to xanthine then uric acid. The reduced production of uric acid r... View More
Mode of Action
Administration Should be taken with food. Take immediately after meals.
Hyperuricaemia, Uric acid nephropathy, Cancer therapy-induced hyperuricaemia, Gout, Recurrent renal stones
Renal impairment: Haemodialysis: Administer dose after session or administer 50% supplemental dose. CrCl (ml/min) 10-20 200 mg daily. <3 100 mg da... View More
Pregnancy Category Note
1-10% Rash (1.5%),Nausea (1.3%),Renal failure (1.2%),Vomiting (1.2%) Frequency Not Defined Amblyopia,Arthralgias,Blood dyscrasias,Bronchospasm,Card... View More
Hypersensitivity; acute attack of gout.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More