Astin20mg
Tablet
Jayson Pharmaceuticals Ltd.
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| Alcohol | CAUTION Caution is advised when consuming alcohol with Astin. Please consult your doctor. |
| Pregnancy | UNSAFE Astin is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effect... View More |
| Breastfeeding | UNSAFE Astin is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | SAFE Astin does not usually affect your ability to drive. |
| Kidney | SAFE IF PRESCRIBED Astin is safe to use in patients with kidney disease. No dose adjustment of Astin is recommended.
However, inform your doctor if you have any underlying... View More |
| Liver | CAUTION Astin should be used with caution in patients with liver disease. Dose adjustment of Astin may be needed. Please consult your doctor.
Use of Astin is no... View More |
Introduction
Astin belongs to a group of medicines called statins. It is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fatty su... View More
Uses of Astin
- High cholesterol
- Prevention of heart attack
Side effects of Astin
- Constipation
- Headache
- Muscle pain
How to use Astin
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Astin may be taken with or... View More
How Astin works
Astin is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It t... View More
What if you forget to take Astin?
If you miss a dose of Astin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your reg... View More
- In general, Astin is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
- Inform your doctor if you experience fatigue, muscle weakness or muscle pain.
- Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver proble... View More
- Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your... View More
- Do not take Astin if you are pregnant, planning a pregnancy or breastfeeding.
Indication
Oral Mixed dyslipidaemia, Heterozygous familial hypercholesterolaemia, Nonfamilial hypercholesterolaemia Adult: Initially, 10 or 20 mg once daily, may... View More
Administration
May increase risk of myopathy and rhabdomyolysis w/ CYP3A4 potent inhibitor (e.g. HIV or HCV protease inhibitors, itraconazole, clarithromycin), fenofib... View More
Adult Dose
Patients who consume substantial quantities of alcohol. History of liver disease. Patients with risk factors for myopathy or rhabdomyolysis. Hypothyroid... View More
Renal Dose
Atorvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyses the conversion of HMG-CoA to mevalonate. This results in the induction ... View More
Contraindication
Oral Mixed dyslipidaemia, Heterozygous familial hypercholesterolaemia, Nonfamilial hypercholesterolaemia Child: Heterozygous familial hypercholesterol... View More
Mode of Action
Atorvastatin can be administered as a single dose at any time of the day, with or without food. Avoid excessive consumption (>1 L/day) of grapefruit jui... View More
Precaution
Primary hypercholesterolemia (heterozygous familial and nonfamilial), Mixed Dyslipidemia, Homozygous familial hypercholesterolemia, Hypertriglyceridemi... View More
Side Effect
Renal Insufficiency: Renal disease does not affect the plasma concentrations or LDL-C reduction of atorvastatin; thus, dosage adjustment in patients wit... View More
Pregnancy Category Note
>10% Diarrhea (5-14%),Nasopharyngitis (4-13%),Arthralgia (4-12%) 1-10% Insomnia (1-5%),Urinary tract infection (4-8%),Nausea (4-7%),Dyspepsia (3-6%... View More
Interaction
Hypersensitivity, active liver disease or unexplained persistent elevations of serum transaminase, porphyria, pregnancy, lactation.
Alternative brand for Astin
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More