Introduction
Asunra 100 is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the b... View More
Uses of Asunra 100
Side effects of Asunra 100
How to use Asunra 100
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Asunra 100 is to be taken ... View More
How Asunra 100 works
Asunra 100 traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.
What if you forget to take Asunra 100?
If you miss a dose of Asunra 100, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to you... View More
Indication
Chronic iron overload.
Administration
Should be taken on an empty stomach. Take on an empty stomach at least 30 min before meals preferably at the same time daily. Disperse tab completely by... View More
Adult Dose
Transfusional Hemosiderosis Indicated for treatment of chronic iron overload caused by blood transfusion 20 mg/kg PO qDay; may increase by 5-10 mg inc... View More
Child Dose
Transfusional Hemosiderosis Indicated for treatment of chronic iron overload caused by blood transfusion <2 years: Safety and efficacy not established... View More
Renal Dose
Renal Impairment Baseline renal impairment CrCl 40-60 mL/min: Reduce starting dose by 50% Serum Cr >2 xULN or CrCl <40 mL/min: Do not use
Contraindication
Hypersensitivity.
Mode of Action
Deferasirox is an orally active chelator that is selective for iron (as Fe3+ ion). It is a tridentate ligand that binds iron with high affinity in a 2:1... View More
Precaution
Monitor renal function and CBC before starting treatment and regularly during treatment; may need to reduce dose or stop treatment if serum creatinine l... View More
Side Effect
>10% Serum creatinine increase (dose related; 7-38%),Abdominal pain (21-28%),Nausea (11-23%),Vomiting (10-21%),Diarrhea (12-20%),Proteinuria (19%),Pyre... View More
Pregnancy Category Note
Pregnancy There are no studies with use in pregnant women to inform drug-associated risks; administration of deferasirox to rats during pregnancy resul... View More
Interaction
Not to be used with aluminium-containing antacids as it may chelate aluminium.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More