Avifanz600mg
Tablet
Beximco Pharmaceuticals Ltd.
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| Alcohol | CAUTION Caution is advised when consuming alcohol with Avifanz. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Avifanz is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in s... View More |
| Breastfeeding | SAFE IF PRESCRIBED Avifanz is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. |
| Driving | UNSAFE Avifanz may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. |
| Kidney | SAFE IF PRESCRIBED Avifanz is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Avifanz may not be needed in th... View More |
| Liver | CAUTION Avifanz should be used with caution in patients with liver disease. Dose adjustment of Avifanz may be needed. Please consult your doctor.
Use of Avifanz... View More |
Introduction
Avifanz belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (a... View More
Uses of Avifanz
- HIV infection
Side effects of Avifanz
- Headache
- Dizziness
- Agranulocytosis (deficiency of granulocytes in the blood)
- Insomnia (difficulty in sleeping)
- Sleepiness
- Vomiting
- Allergic reaction
- Nausea
- Abnormal dreams
- Fatigue
- Increased liver enzymes
- Anxiety
- Fever
- Itching
- Difficulty in paying attention
- Increased triglyceride level in blood
- Rash
How to use Avifanz
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avifanz is to be taken emp... View More
How Avifanz works
Avifanz prevents the multiplication of HIV virus in human cells, thereby stopping the HIV virus from producing new viruses.
- Avifanz is used in combination with other medicines for the treatment of HIV (human immunodeficiency virus).
- Take it on an empty stomach, preferably at bedtime to reduce side effects.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
- Your doctor may check your liver function regularly. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
- You might experience dizziness or abnormal dreams during initial days of treatment. Consult with a doctor if it bothers you or does not go away.
- Use a reliable method of contraception to prevent pregnancy while taking this medicine.
Indication
HIV infection
Administration
Should be taken on an empty stomach. Take on an empty stomach, preferably at bedtime.
Adult Dose
Oral HIV infection Adult: Combined with other antiretrovirals: 600 mg once daily. Dosing at bedtime recommended during 1st 2-4 wk of therapy to improv... View More
Child Dose
Oral HIV infection Child: Combined with other antiretrovirals: >3 yr, 10-14 kg: 200 mg; 15-19 kg: 250 mg; 20-24 kg: 300 mg; 25-32.4 kg: 350 mg... View More
Renal Dose
Renal impairment: No dosage adjustment needed
Contraindication
Severe hepatic impairment; hypersensitivity; lactation.
Mode of Action
Efavirenz, a non-nucleoside reverse transcriptase inhibitor with activity against HIV, blocks the RNA-dependent and DNA-dependent polymerase activities ... View More
Precaution
Mild to moderate liver disease; renal impairment. Monitor liver enzymes and cholesterol. Discontinue if severe skin rash or fever develops; known or sus... View More
Side Effect
>10% Total cholesterol increased (20-40%),Diarrhea (3-14%, children up to 39%),HDL increased (25-35%),Dizziness (28.1%),Rash (5-26%),Fever (children 21... View More
Pregnancy Category Note
Pregnancy Category: D Lactation: Unknown if distributed in human milk; the CDC advises HIV-infected women not to breastfeed to avoid postnatal transm... View More
Interaction
Hormonal contraceptives; antibacterial e.g. rifampicin, rifabutin, clarithromycin; enzyme inducers. St. John's wort may decrease serum level. Ethanol (h... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More