Avifanz belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (a... View More
Uses of Avifanz
Side effects of Avifanz
How to use Avifanz
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avifanz is to be taken emp... View More
How Avifanz works
Avifanz prevents the multiplication of HIV virus in human cells, thereby stopping the HIV virus from producing new viruses.
Should be taken on an empty stomach. Take on an empty stomach, preferably at bedtime.
Oral HIV infection Adult: Combined with other antiretrovirals: 600 mg once daily. Dosing at bedtime recommended during 1st 2-4 wk of therapy to improv... View More
Oral HIV infection Child: Combined with other antiretrovirals: >3 yr, 10-14 kg: 200 mg; 15-19 kg: 250 mg; 20-24 kg: 300 mg; 25-32.4 kg: 350 mg... View More
Renal impairment: No dosage adjustment needed
Severe hepatic impairment; hypersensitivity; lactation.
Mode of Action
Efavirenz, a non-nucleoside reverse transcriptase inhibitor with activity against HIV, blocks the RNA-dependent and DNA-dependent polymerase activities ... View More
Mild to moderate liver disease; renal impairment. Monitor liver enzymes and cholesterol. Discontinue if severe skin rash or fever develops; known or sus... View More
>10% Total cholesterol increased (20-40%),Diarrhea (3-14%, children up to 39%),HDL increased (25-35%),Dizziness (28.1%),Rash (5-26%),Fever (children 21... View More
Pregnancy Category Note
Pregnancy Category: D Lactation: Unknown if distributed in human milk; the CDC advises HIV-infected women not to breastfeed to avoid postnatal transm... View More
Hormonal contraceptives; antibacterial e.g. rifampicin, rifabutin, clarithromycin; enzyme inducers. St. John's wort may decrease serum level. Ethanol (h... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More