Introduction
Avilam is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of virus in human cells. ... View More
Uses of Avilam
Side effects of Avilam
How to use Avilam
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avilam may be taken with o... View More
How Avilam works
Avilam is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up... View More
What if you forget to take Avilam?
If you miss a dose of Avilam, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More
Indication
HIV infection, Chronic hepatitis B
Administration
May be taken with or without food.
Adult Dose
Oral HIV infection Adult: 150 mg bid or 300 mg once daily, in combination with other antiretrovirals. Chronic hepatitis B Adult: 100 mg once daily... View More
Child Dose
Oral HIV infection Child: 3 mth-12 yr: 4 mg/kg bid. Max: 300 mg/day. Chronic hepatitis B Child: >2 yr: 3 mg/kg once daily. Max: 100 mg/day.
Renal Dose
Oral HIV infection Renal impairment: Dialysis patients: Not recommended. CrCl (ml/min) 30-49 1st dose 150 mg, then 150 mg once daily. 15-29 1st do... View More
Contraindication
Hypersensitivity. Lactation.
Mode of Action
Lamivudine, a nucleoside analogue, is phosphorylated in the body to the active triphosphate form. In the active form, it inhibits hepatitis B virus poly... View More
Precaution
Discontinue use if there is rapid increase in aminotransferase levels, progressive hepatomegaly, or metabolic or lactic acidosis of unknown origin. Disc... View More
Side Effect
>10% Cough,Diarrhea,Fatigue & malaise,Fever (peds),Headache,Musculoskeletal pain,Nausea,Nervous system neuropathy,Pancreatitis,Peripheral neuropathy,Na... View More
Interaction
Renal excretion may be inhibited by high doses of trimethoprim (co-trimoxazole). May antagonise the antiviral action of zalcitabine.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More