Salazopyrin EN500mg
Tablet
Pfizer Limited
Additional Offers
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| Alcohol | UNSAFE It is unsafe to consume alcohol with Salazopyrin EN. |
| Pregnancy | SAFE IF PRESCRIBED Salazopyrin EN is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Salazopyrin EN is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.... View More |
| Driving | SAFE Salazopyrin EN does not usually affect your ability to drive. |
| Kidney | CAUTION Salazopyrin EN should be used with caution in patients with kidney disease. Dose adjustment of Salazopyrin EN may be needed. Please consult your doctor.... View More |
| Liver | UNSAFE Salazopyrin EN is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor. |
Introduction
Salazopyrin EN is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondyli... View More
Uses of Salazopyrin EN
- Rheumatoid arthritis
- Ulcerative colitis
- Crohn’s disease
- Ankylosing spondylitis
Side effects of Salazopyrin EN
- Diarrhea
- Gastrointestinal discomfort
- Headache
- Loss of appetite
- Nausea
- Oligospermia (low sperm count)
- Vomiting
- Weight loss
How to use Salazopyrin EN
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Salazopyrin EN is to be ta... View More
How Salazopyrin EN works
Salazopyrin EN is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases... View More
What if you forget to take Salazopyrin EN?
If you miss a dose of Salazopyrin EN, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to... View More
- Take it with food to avoid an upset stomach.
- It may take 6-8 weeks for Sazo 500 Tablet DR to work. Keep taking it as prescribed.
- Drink plenty of fluids while taking Sazo 500 Tablet DR in order to avoid kidney problems such as kidney stones.
- It may cause a deficiency of folic acid. Take the supplements as suggested by the doctor.
- Do not take Sazo 500 Tablet DR if you are allergic to sulfa drugs or aspirin.
- It may discolour your skin, urine, saliva and tears an orange/yellow colour. This is normal and not harmful.
- Regular blood tests to monitor your liver function, kidney function, and the levels of your blood components are required while taking this medicine.
- Do not stop taking the medication suddenly without talking to your doctor.
Indication
Inflammatory bowel disease, Rheumatoid arthritis
Administration
Should be taken with food. Take after meals. Ensure adequate fluid intake.
Adult Dose
Oral Inflammatory bowel disease Adult: Initially, 1-2 g 4 times daily until remission occurs. Maintenance: 2 g/day in divided doses. Rheumatoid art... View More
Child Dose
Oral Inflammatory bowel disease Child: >2 yr: 40-60 mg/kg/day in divided doses. Maintenance: 20-30 mg/kg/day in divided doses. Rheumatoid arthritis... View More
Renal Dose
Renal impairment: CrCl (ml/min) Dosage Recommendation 10-30ml/min Admin twice daily. <10ml/min Admin once daily.
Contraindication
Hypersensitivity to sulphonamides or salicylates, porphyria, <2 yr of age, intestinal or urinary obstruction, blood dycrasias, history of leucopenia wit... View More
Mode of Action
Actual mechanism not determined. Sulphasalazine may have direct anti-inflammatory action in the colon. It also systemically interferes with secretion by... View More
Precaution
Hepatic/renal impairment, G6PD deficiency, allergic bronchial asthma, lactation. Lactation: Excreted into human breast milk; caution with breastfeedi... View More
Side Effect
>10% Anorexia (~33%),Headache (~33%),Nausea (~33%),Vomiting (~33%),Gastric distress (~33%),Apparently reversible oligospermia (~33%) <1% Skin rash,... View More
Pregnancy Category Note
Pregnancy category: B; D if used for prolonged periods or near term; increased potential for kernicterus in the newborn
Interaction
Plasma levels reduced by rifampicin and ethambutol. Interferes with absorption of folic acid. Additive leucopaenia with gold therapy for rheumatoid arth... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More