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Febulas80mg

Tablet
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Delta Pharma Limited
Generic: Febuxostat
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descriptionSafety Advices
AlcoholAlcohol
CAUTION
Caution is advised when consuming alcohol with Febulas. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Febulas may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Febulas is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Febulas may cause side effects which could affect your ability to drive. Febulas may cause dizziness, sleepiness, blurred vision, numbness or tingling s... View More
KidneyKidney
CAUTION
Febulas should be used with caution in patients with severe kidney disease. Dose adjustment of Febulas may be needed. Please consult your doctor. Limite... View More
LiverLiver
CAUTION
Febulas should be used with caution in patients with severe liver disease. Dose adjustment of Febulas may be needed. Please consult your doctor. Limited... View More
descriptionMedical Overview

Introduction

Febulas is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals which can ap... View More

Uses of Febulas

  • Gout

Side effects of Febulas

Common
  • Diarrhea
  • Headache
  • Increased liver enzymes
  • Nausea
  • Skin rash
  • Gout flares

How to use Febulas

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Febulas may be taken with ... View More

How Febulas works

Febulas is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.

What if you forget to take Febulas?

If you miss a dose of Febulas, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More

quick tipsQuick Tips
  • Your doctor has prescribed Febulas to reduce episodes of gout attack.
  • Take it at the same time every day, with or without food.
  • Take plenty of fluids (2-3 litres) daily while on Febulas.
  • When you first start taking this medicine, you might have more gout attacks. Do not stop Febulas on having an acute attack of gout as that could make an... View More
  • Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
  • Stop taking this medicine and inform your doctor straight away if you have symptoms like rash, itchiness, difficulties in breathing, fever or swelling o... View More
descriptionBrief Description

Indication

Gout, Hyperuricemia

Administration

May be taken with or without food. May be taken w/o regard to antacid use.

Adult Dose

Chronic Gout 40 mg/day PO initially; maintenance: 40-80 mg/day; increased if serum uric acid is >6 mg/mL after 2 weeks Hepatic impairment Mild to m... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment Mild to moderate (CrCl 30-89 mL/min): Dosage adjustment not necessary Severe (CrCl <30 mL/min): Data not available; use with caution

Contraindication

Patients being treated with azathioprine, mercaptopurine, or theophylline.

Mode of Action

Febuxostat selectively inhibits xanthine oxidase, the enzyme that catalyses the conversion of hypoxanthine to xanthine to uric acid, thereby decreasing ... View More

Precaution

Cardiovascular death Patients with established cardiovascular (CV) disease treated with febuxostat had a higher rate of CV death compared with those tr... View More

Side Effect

>1% Arthralgia,Elevated liver function test (LFT) results,Liver function abnormalities,Nausea,Rash

Pregnancy Category Note

Pregnancy Limited available data in pregnant women are insufficient to inform a drug associated risk of adverse developmental outcomes Animal data ... View More

Interaction

May increase plasma conc of mercaptopurine, azathioprine. Alteration of metabolism of xanthine oxidase substrate drugs (eg theophylline).

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More