Bacilex200mg

Indication

Acute uncomplicated cystitis, Chronic or recurrent bacteriuria

Adult Dose

Oral Acute uncomplicated cystitis Adult: Initially 400 mg followed by 200 mg tid for 8 doses. Chronic or recurrent bacteriuria Adult: 400 mg 3-4 t... View More

Child Dose

Oral Acute uncomplicated cystitis Child: <40 kg with UTI: 20-40 mg/kg/day in 3-4 divided doses. Chronic or recurrent bacteriuria Child: <40 kg wit... View More

Contraindication

Hypersensitivity, porphyria.

Mode of Action

Pivmecillinam has the antimicrobial activity of mecillinam to which it is hydrolysed in vivo. It interferes with the synthesis of bacterial cell wall. I... View More

Precaution

Very high doses in poor renal function (risk of neurotoxicity) or heart failure. Avoid contact, skin sensitization may occur. Monitor serum K concentrat... View More

Side Effect

Hypersensitivity reactions including uticaria; fever; joint pains; rashes; angioedema; serum sickness-like reactions; haemolytic anaemia; interstitial n... View More

Interaction

Probenecid prolongs T1/2 of pivmecillinam. May cause prolonged bleeding when taken with anticoagulants. May decrease the efficacy of oral contraceptives... View More