Introduction
Barbit belongs to a class of medicines called barbiturates. It is a prescription medicine used to treat and prevent epilepsy (seizures). They also have ... View More
Uses of Barbit
Side effects of Barbit
How to use Barbit
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Barbit may be taken with o... View More
How Barbit works
Barbit controls seizures or fits by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerv... View More
Indication
Status epilepticus, Partial seizures, Sedation, Generalised tonic-clonic seizures, Hypnotic, Preoperative sedation
Administration
Reconstitution: Dilute w/ most IV infusion soln (e.g. NaCl 0.45% or 0.9%, lactated Ringer's, dextrose 5%, Ringer's). IV Administration Slow inject... View More
Adult Dose
Parenteral Status epilepticus ; Emergency management of acute seizures Adult: As phenobarbital Na: 200-600 mg. OR 15-18 mg/kg IV loading dose infused ... View More
Child Dose
Parenteral Status epilepticus ; Emergency management of acute seizures Child: As phenobarbital Na: 100-400 mg. OR Infants and children: 15-20 mg/kg ... View More
Renal Dose
Renal impairment: Reduce dose. Severe: Contraindicated.
Contraindication
Severe renal and hepatic disorders. Severe respiratory depression, dyspnoea or airway obstruction; porphyria. Pregnancy.
Mode of Action
Phenobarbitone is a short-acting barbiturate. It depresses the sensory cortex, reduces motor activity, changes cerebellar function, and produces drowsin... View More
Precaution
Patient w/ history or sedative/hypnotic addiction; resp disease, depression or suicidal tendencies, hypoadrenalism. Avoid abrupt withdrawal. Mild to mod... View More
Side Effect
Common Ataxia,Dizziness,Drowsiness,Dysarthria,Fatigue,Headache,Irritability,Nystagmus,Paresthesia restlessness,Vertigo Geriatric patients: Excitement,... View More
Interaction
May enhance the hepatotoxic potential of paracetemaol overdoses. May decrease levels/effects of various CYP isoenzyme substrates e.g. teniposide, methot... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More