Endoxan Coated50mg
Tablet
Sanofi Bangladesh Ltd.
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| Alcohol | UNSAFE It is unsafe to consume alcohol with Endoxan Coated. |
| Pregnancy | CONSULT YOUR DOCTOR Endoxan Coated is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe ... View More |
| Breastfeeding | UNSAFE Endoxan Coated is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | UNSAFE Endoxan Coated may cause side effects which could affect your ability to drive.
Endoxan Coated may cause undesirable effects (e.g., dizziness, blurred v... View More |
| Kidney | CAUTION Endoxan Coated should be used with caution in patients with severe kidney disease. Dose adjustment of Endoxan Coated may be needed. Please consult your ... View More |
| Liver | CAUTION Endoxan Coated should be used with caution in patients with liver disease. Dose adjustment of Endoxan Coated may be needed. Please consult your doctor. |
Introduction
Endoxan Coated is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children a... View More
Uses of Endoxan Coated
- Cancer
- Nephrotic syndrome
Side effects of Endoxan Coated
- Vomiting
- Nausea
- Hair loss
- Fever
- Blood in urine
- Diarrhea
- Decreased white blood cell count (neutrophils)
How to use Endoxan Coated
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endoxan Coated is to be ta... View More
How Endoxan Coated works
Endoxan Coated is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, t... View More
- Endoxan Coated helps in the treatment of cancer.
- Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
- Take it with food if you experience irritation of the stomach, preferably in the morning.
- Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
- You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
- Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
- Do not take Endoxan Coated if you are pregnant or breastfeeding.
- Use effective contraception method to prevent pregnancy while taking this medicine.
Indication
Bone marrow transplantation, malignancies, lymphomas, brain cancer, leukemia, systemic lupus erythematosus, minimal change disease, severe rheumatoid ar... View More
Administration
Should be taken on an empty stomach. Preferably taken on an empty stomach, but may be taken w/ meals to minimise GI irritation. Ensure adequate fluid in... View More
Adult Dose
Malignant Diseases IV (intermittent therapy): 40-50 mg/kg (400-1800 mg/m²) divided over 2-5 days; may be repeated at intervals of 2-4 weeks IV (cont... View More
Child Dose
Malignant Diseases IV (intermittent therapy): 40-50 mg/kg (400-1800 mg/m²) divided over 2-5 days; may be repeated at intervals of 2-4 weeks IV (cont... View More
Contraindication
Bladder haemorrhage. Patients with bone-marrow aplasia, acute infection, drug- or radiation-induced urothelial toxicity. Porphyria. Pregnancy and lactat... View More
Mode of Action
Cyclophosphamide is a prodrug which is converted in the body to the active metabolites. It acts at any stage of the cell cycle but its main action is bl... View More
Precaution
Blood disorders. Elderly or debilitated patients. Diabetic patients. Renal or hepatic impairment or who have gone adrenaloctomy. Previous treatment with... View More
Side Effect
Alopecia, skin and nails hyperpigmentation, nausea and vomiting, mucositis, inappropriate antidiuretic hormone secretion, carbohydrate metabolism distur... View More
Pregnancy Category Note
Pregnancy Based on mechanism of action and published reports of effects in pregnant patients or animals, drug can cause fetal harm when administered to... View More
Interaction
Increased risk of cardiotoxicity w/ doxorubicin or other cardiotoxic drugs. May increase incidence of mucositis w/ protease inhibitors. May increase hae... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More