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Dieta Plus 230mg+2mg

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Pacific Pharmaceuticals Ltd.
Generic: Glimepiride + Pioglitazone
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descriptionSafety Advices
It is unsafe to consume alcohol with Dieta Plus 2.
Dieta Plus 2 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the devel... View More
Dieta Plus 2 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby... View More
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Dieta Plus 2 should be used with caution in patients with kidney disease. Dose adjustment of Dieta Plus 2 may be needed. Please consult your doctor. Use... View More
Dieta Plus 2 should be used with caution in patients with liver disease. Dose adjustment of Dieta Plus 2 may be needed. Please consult your doctor. Use ... View More
descriptionMedical Overview


Dieta Plus 2 is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sug... View More

Uses of Dieta Plus 2

  • Type 2 diabetes mellitus

Side effects of Dieta Plus 2

  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Taste change
  • Diarrhea
  • Stomach pain
  • Headache
  • Edema (swelling)
  • Weight gain
  • Blurred vision
  • Bone fracture
  • Respiratory tract infection

How to use Dieta Plus 2

Use it as advised by your doctor or check the label for directions before use. Dieta Plus 2 is to be taken with food.

How Dieta Plus 2 works

Dieta Plus 2 is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide bet... View More

quick tipsQuick Tips
  • Take it with food to lower your chance of having an upset stomach.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxi... View More
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing o... View More
descriptionBrief Description


Type 2 DM

Adult Dose

Oral Type 2 diabetes mellitus Adult: 30 mg/2 mg, OR 30 mg/4 mg: Initially, 1 tab once daily then titrate gradually as needed. Elderly: Should start... View More

Renal Dose

Renal Impairment CrCl <22 mL/min: 1 mg/day glimepiride PO prior to initiating glimepiride/pioglitazone; titrate conservatively to avoid hypoglycemia B... View More


History of allergic reaction to sulfonamide derivative. Patient w/ established CHF (NYHA class III or IV). Not intended for treatment of type 1 DM or di... View More

Mode of Action

Pioglitazone, a thiazolidinedione, reduces blood glucose by improving target cell response to insulin w/o increasing pancreatic insulin secretion and is... View More


Pioglitazone, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medication... View More

Side Effect

>10% Peripheral edema (6-12%),Upper respiratory tract infection (12-15%),Weight gain (9-13%),Hypoglycemia (13-16%) 1-10% Anemia (<2%),Limb pain (4-... View More


Increased plasma levels w/ CYP2C8 inhibitors (e.g. gemfibrozil) and CYP2C9 inhibitors (e.g. fluconazole). Decreased plasma levels w/ CYP2C8 inducers (e.... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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