Bortez 11mg/vial
Injection
Beacon Pharmaceuticals Ltd.
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| Alcohol | UNSAFE Bortez 1 may cause excessive drowsiness with alcohol. |
| Pregnancy | CONSULT YOUR DOCTOR Bortez 1 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in ... View More |
| Breastfeeding | UNSAFE Bortez 1 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | UNSAFE Bortez 1 may cause side effects which could affect your ability to drive.
Bortez 1 might cause tiredness, dizziness, fainting, or blurred vision which m... View More |
| Kidney | CAUTION Bortez 1 should be used with caution in patients with severe kidney disease. Dose adjustment of Bortez 1 may be needed. Please consult your doctor.
Limi... View More |
| Liver | CAUTION Bortez 1 should be used with caution in patients with liver disease. Dose adjustment of Bortez 1 may be needed. Please consult your doctor. |
Introduction
Bortez 1 is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer ce... View More
Uses of Bortez 1
- Multiple myeloma
- Mantle-cell lymphoma
Side effects of Bortez 1
- Low blood platelets
- Fatigue
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Psychiatric disturbances
- Nausea
- Vomiting
- Loss of appetite
- Fever
- Anemia (low number of red blood cells)
- Diarrhea
- Decreased appetite
- Decreased white blood cell count (neutrophils)
- Constipation
How to use Bortez 1
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Bortez 1 works
Bortez 1 is an anti-cancer medication. It works by blocking or slowing the breakdown of proteins in cells. As a result, there is an increase in a number... View More
What if you forget to take Bortez 1?
If you miss a dose of Bortez 1, please consult your doctor.
- Before taking bortezomib, consult your doctor if you have any of the following disease conditions: disease of liver, kidney, heart or infections like fe... View More
- Drink plenty of fluids every day during your treatment with bortezomib.
- Tell your doctor if you are or planning to become pregnant or are breastfeeding.
- Consult your doctor if you have signs of serious brain infection such as memory loss, trouble in thinking, difficulty with walking or loss of vision.
- Do not drive or operate machinery after taking bortezomib as it may cause tiredness, dizziness, fainting or blurred vision.
Indication
Mantle Cell Lymphoma, Multiple Myeloma,
Administration
IV or SC Preparation Reconstitute vial with 0.9% NaCl IV administration: Add 3.5 mL to vial for final concentration of 1 mg/mL SC administration: 2.5... View More
Adult Dose
Mantle Cell Lymphoma Indicated for treatment of patients with mantle cell lymphoma as first-line in previously untreated patients or those who have rel... View More
Contraindication
Hypersensitivity. Child. Pregnancy and lactation.
Mode of Action
Bortezomib is a reversible inhibitor of the chymotrypsin-like activity of the 26-S proteasome. It prevents targeted proteolysis that affects multiple si... View More
Precaution
Hepatic or renal impairment; history of syncope, orthostatic hypotension; dehydration. Impairs ability to drive or operate machinery. Monitor for sympto... View More
Side Effect
>10% Asthenia (61-65%) Nausea (61-65%) Diarrhea (51-55%) Anorexia (41-45%) Constipation (41-45%) Thrombocytopenia (41-45%) Peripheral neuropathy ... View More
Pregnancy Category Note
Pregnancy Based on mechanism of action and findings in animals, therapy can cause fetal harm when administered to a pregnant woman; there are no stud... View More
Interaction
Concurrent use of amiodarone, antivirals, isoniazid, nitrofurantoin, statins may increase the chance of peripheral neuropathy. Concurrent use of antihyp... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More