Firmagon120mg
Injection
Radiant Pharmaceuticals Ltd.
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| Alcohol | CAUTION Caution is advised when consuming alcohol with Firmagon. Please consult your doctor. |
| Pregnancy | UNSAFE Firmagon is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful eff... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Information regarding the use of Firmagon during breastfeeding is not available. Please consult your doctor. |
| Driving | UNSAFE Firmagon may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. |
| Kidney | CONSULT YOUR DOCTOR There is limited information available on the use of Firmagon in patients with kidney disease. Please consult your doctor.
A cautious use of Firmagon is... View More |
| Liver | CAUTION Firmagon should be used with caution in patients with severe liver disease. Dose adjustment of Firmagon may be needed. Please consult your doctor.
No do... View More |
Introduction
Firmagon is used in the treatment of advanced prostate cancer. It works by lowering the amount of testosterone produced in the body and restricts the gr... View More
Uses of Firmagon
- Prostate cancer
Side effects of Firmagon
- Injection site reactions (pain, swelling, redness)
- Weight gain
- Hot flashes
- Increased liver enzymes
- Low sexual desire
- Erectile dysfunction
How to use Firmagon
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Firmagon works
Firmagon lowers the amount of testosterone (a male hormone) produced by the body. This may slow or stop the spread and growth of prostate cancer cells t... View More
What if you forget to take Firmagon?
If you miss a dose of Firmagon, please consult your doctor.
- Firmagon helps in the treatment of advanced hormone-dependent prostate cancer.
- It is give by injection under the skin (subcutaneously), usually in the stomach area.
- It may cause dizziness and blurred vision. Do not drive or do anything that requires mental focus until you know how it affects you.
- It may cause hot flashes. Try wearing loose clothing and avoid alcohol, caffeine, and spicy foods.
- Inform your doctor if you are diabetic or have problems with your heart, kidney or liver.
- Your doctor may check the level of prostate specific antigen (PSA) in your blood. This is done to monitor how well Firmagon is working for you. A decrea... View More
Indication
Hormone-dependent Advanced Prostate Carcinoma (Stage D)
Administration
Initiation pack contains 2 vials each with 120 mg per vial & 6 mL sterile water for injection diluent Withdraw 3 mL of sterile water for injection di... View More
Adult Dose
Subcutaneous Advanced prostate cancer Adult: Loading dose: As 40 mg/mL solution: 240 mg (given as 2 separate injections of 120 mg). Maintenance: As 20... View More
Renal Dose
Renal Impairment >50 mL/min: Dose adjustment not necessary <50 mL/min: Use caution
Contraindication
Hypersensitivity. Pregnancy and lactation.
Mode of Action
Degarelix, a synthetic decapeptide, reversibly and competitively binds to gonadotropin-releasing hormone (GnRH) receptors in the anterior pituitary glan... View More
Precaution
Patient with congenital long QT syndrome, history of or risk factors for QT prolongation (e.g. cardiac failure, electrolyte imbalance) and CV disease; d... View More
Side Effect
>10% Hot flashes (26%) Injection site erythema (17%) Injection site pain (28%) Weight gain (11%) Elevated liver enzymes (10%) 1-10% (selected) ... View More
Pregnancy Category Note
Pregnancy Category: X Lactation: excretion in milk unknown/not recommended
Interaction
Increased risk of QT prolongation with class IA (e.g. disopyramide) or class III (e.g. amiodarone) antiarrhythmics, antipsychotics, methadone and moxifl... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More