Rezoven10mg

Indication

Adult: PO: (age > 12 year) 10 mg, once daily.

Administration

Increased risk of nephrotoxicity with nephrotoxic drugs e.g. aminoglycosides, ciclosporin, NSAIDs, vancomycin, tacrolimus. Ibuprofen increases bioavaila... View More

Adult Dose

Pregnancy; elderly; child; renal or hepatic impairment. HIV antibody testing to be performed before initiation due to possible resistance development in... View More

Renal Dose

Adefovir dipivoxil is an acyclic nucleoside reverse transciptase inhibitor. The diester function is hydrolyzed and subsequently phosphorylated to the ac... View More

Mode of Action

Taken orally, without regard to food.

Precaution

Chronic hepatitis B

Side Effect

Renal impairment: Haemodialysis patients: 10 mg every 7 days after dialysis. CrCl (ml/min) 30-49 10 mg every 48 hr. 10-29 10 mg every 72 hr.

Pregnancy Category Note

>10% Hematuria (11% vs 10% in placebo-treated),Asthenia (13% vs. 14% placebo),Hepatitis exacerbation (25%) 1-10% Nausea (5%),Flatulence (4%),Diarrh... View More

Interaction

Adefovir Dipivoxil is contraindicated in patients with previously demonstrated hypersensitivity to any of the components of the product.