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Generic: Lamivudine
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descriptionSafety Advices
Caution is advised when consuming alcohol with Zeffix. Please consult your doctor.
Zeffix may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing ... View More
Zeffix is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Zeffix does not usually affect your ability to drive.
Zeffix should be used with caution in patients with kidney disease. Dose adjustment of Zeffix may be needed. Please consult your doctor.
Zeffix is safe to use in patients with liver disease. No dose adjustment of Zeffix is recommended.
descriptionMedical Overview


Zeffix is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of virus in human cells. ... View More

Uses of Zeffix

  • HIV infection
  • Chronic hepatitis B virus (HBV) infection

Side effects of Zeffix

  • Headache
  • Runny nose
  • Nausea
  • Fever
  • Diarrhea

How to use Zeffix

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zeffix may be taken with o... View More

How Zeffix works

Zeffix is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up... View More

What if you forget to take Zeffix?

If you miss a dose of Zeffix, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More

quick tipsQuick Tips
  • You have been prescribed Lamivir HBV Tablet for the treatment of chronic hepatitis B virus (HBV) infection.
  • In combination with other medicines, it is used for the treatment of HIV infections.
  • Take it with food, as this increases the absorption of the medicine into the body.
  • Lamivir HBV Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may still develop infections or other illnesses associated with viral infection while taking this medication.
  • You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
  • During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepat... View More
descriptionBrief Description


HIV infection, Chronic hepatitis B


May be taken with or without food.

Adult Dose

Oral HIV infection Adult: 150 mg bid or 300 mg once daily, in combination with other antiretrovirals. Chronic hepatitis B Adult: 100 mg once daily... View More

Child Dose

Oral HIV infection Child: 3 mth-12 yr: 4 mg/kg bid. Max: 300 mg/day. Chronic hepatitis B Child: >2 yr: 3 mg/kg once daily. Max: 100 mg/day.

Renal Dose

Oral HIV infection Renal impairment: Dialysis patients: Not recommended. CrCl (ml/min) 30-49 1st dose 150 mg, then 150 mg once daily. 15-29 1st do... View More


Hypersensitivity. Lactation.

Mode of Action

Lamivudine, a nucleoside analogue, is phosphorylated in the body to the active triphosphate form. In the active form, it inhibits hepatitis B virus poly... View More


Discontinue use if there is rapid increase in aminotransferase levels, progressive hepatomegaly, or metabolic or lactic acidosis of unknown origin. Disc... View More

Side Effect

>10% Cough,Diarrhea,Fatigue & malaise,Fever (peds),Headache,Musculoskeletal pain,Nausea,Nervous system neuropathy,Pancreatitis,Peripheral neuropathy,Na... View More


Renal excretion may be inhibited by high doses of trimethoprim (co-trimoxazole). May antagonise the antiviral action of zalcitabine.

Alternative brand for Zeffix
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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