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Sharif Pharmaceuticals Ltd.
Generic: Clobetasol Propionate 0.05% topical
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descriptionSafety Advices
No interaction found/established
Dersole may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing... View More
Dersole is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
No interaction found/established
No interaction found/established
No interaction found/established
descriptionMedical Overview


Dersole belongs to a group of medicines called steroids. It is used to treat various skin conditions such as dermatitis, eczema, and allergies. It works... View More

Uses of Dersole

  • Dermatitis
  • Eczema
  • Allergic skin conditions

Side effects of Dersole

  • Thinning of skin
  • Application site reactions (burning, irritation, itching and redness)

How to use Dersole

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and ... View More

How Dersole works

Dersole is a steroid. It works by blocking the production of certain chemical messengers that make the skin red, swollen and itchy.

quick tipsQuick Tips
  • Dersole is used to treat redness, swelling, itching, and discomfort of various skin conditions.
  • It should be applied to the affected areas as a thin film two or three times daily, or as advised by your doctor.
  • Don't use it more often or for longer than advised by your doctor.
  • Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • If you think the area of skin you are treating has become infected you should stop using Dersole and consult your doctor.
  • Consult your doctor if your skin condition has not improved after four weeks of treatment. Do not use it for more than 4 consecutive weeks at a time.
descriptionBrief Description


Corticosteroid-responsive Dermatoses, Psoriasis, Scalp Psoriasis, Plaque-type Psoriasis, Vitiligo, Eczema, Alopecia areata, Herpes labialis, Lichen scle... View More

Adult Dose

Corticosteroid-responsive Dermatoses Cream: Apply thin layer to affected areas q12hr and rub in gently and completely; not to exceed 50 g/week Scalp... View More

Child Dose

<12 years Safety & efficacy not established >12 years Corticosteroid-responsive Dermatoses Cream: Apply thin layer to affected areas q12hr and rub... View More


Childn <12 yrs. Long-term treatment of ulcerative conditions, rosacea, pruritus; It is contraindicated in rosacea, acne vulgaris, perioral dermatitis, p... View More

Mode of Action

Clobetasol is a very potent corticosteroid used in short-term treatment of various inflammatory skin conditions. Corticosteroids decrease inflammation b... View More


Long-term continuous topical therapy should be avoided where possible, particularly in infants and children, as adrenal suppression can occur readily ev... View More

Side Effect

Perioral dermatitis, striae esp in flexures. Dermal and epidermal atrophy esp on the face, steroid purpura. Burning, Cracking/fissuring of the skin, Ery... View More

Pregnancy Category Note

Pregnancy Safety data on clobetasol in pregnant woman is not available Published data report a significantly increased risk of low birthweight with th... View More


Increased systemic exposure w/ CYP3A4 inhibitors (eg ritonavir & itraconazole).

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More