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Actine 55mg

Tablet
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Aristopharma Limited
Generic: Glipizide
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Actine 5.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Actine 5 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developin... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Actine 5 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Mo... View More
DrivingDriving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Actine 5 should be used with caution in patients with severe kidney disease. Dose adjustment of Actine 5 may be needed. Please consult your doctor. Thes... View More
LiverLiver
CAUTION
Actine 5 should be used with caution in patients with severe liver disease. Dose adjustment of Actine 5 may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Actine 5 is a medicine used to treat type 2 diabetes mellitus in adults. It belongs to a group of medicines called sulfonylureas and helps control blood... View More

Uses of Actine 5

  • Type 2 diabetes mellitus

Side effects of Actine 5

Common
  • Dizziness
  • Diarrhea
  • Nervousness
  • Tremor
  • Hypoglycemia (low blood glucose level)
  • Flatulence

How to use Actine 5

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Actine 5 is to be taken em... View More

How Actine 5 works

Actine 5 is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

What if you forget to take Actine 5?

You should skip a dose of Actine 5 if a meal is skipped, and add a dose of medicine if you eat an extra meal.

quick tipsQuick Tips
  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Be careful while driving or operating machinery until you know how Actine 5 affects you.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxie... View More
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing ... View More
descriptionBrief Description

Indication

Type 2 DM

Administration

Immediate-release: Should be taken on an empty stomach. Take ½ hr before meals. Extended-release: Should be taken with food. Swallow whole, do not chew... View More

Adult Dose

Oral Type 2 diabetes mellitus Adult: Initially, 2.5-5 mg daily as a single dose. Adjust at intervals of several days in increments of 2.5-5 mg daily. ... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment: Not studied; if GFR <50 mL/min, may decrease dose by 50% Severe: Contraindicated.

Contraindication

Hypersensitivity. Type 1 DM; ketoacidosis; severe renal or hepatic insufficiency. Pregnancy, lactation.

Mode of Action

Glipizide stimulates insulin release from pancreatic ?-cells and reduces glucose output from the liver. It also increases insulin sensitivity at periphe... View More

Precaution

Hypoglycaemia, stress, elderly. Thyroid impairment; moderate hepatic or renal impairment. Monitor blood glucose concentration. Lactation: Not known i... View More

Side Effect

GI upsets, diarrhoea, nausea; allergic skin reactions, leucopenia, thrombocytopenia, agranulocytosis, hyponatraemia; jaundice; haemolytic anaemia, pancy... View More

Interaction

Increased plasma concentration w/ certain antifungals (e.g. miconazole, fluconazole). Protein-bound drugs (e.g. NSAIDs, other sulfonamides, oral anticoa... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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