Arofrez2.5mg
Tablet
Healthcare Pharmaceuticals Ltd.
Additional Offers
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| Alcohol | SAFE Consuming alcohol with Arofrez does not cause any harmful side effects. |
| Pregnancy | UNSAFE Arofrez is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effe... View More |
| Breastfeeding | UNSAFE Arofrez is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | UNSAFE Arofrez may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. |
| Kidney | SAFE IF PRESCRIBED Arofrez is safe to use in patients with kidney disease. No dose adjustment of Arofrez is recommended.
However, there is limited information on the use o... View More |
| Liver | CAUTION Arofrez should be used with caution in patients with liver disease. Dose adjustment of Arofrez may be needed. Please consult your doctor. |
Introduction
Arofrez is used alone or with other treatments, such as surgery or radiation, to treat early breast cancer in postmenopausal women. It can also be used ... View More
Uses of Arofrez
- Breast cancer
- Infertility due to anovulation
Side effects of Arofrez
- Fatigue
- Hypercholesterolemia (high cholesterol)
- Increased sweating
How to use Arofrez
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Arofrez may be taken with ... View More
How Arofrez works
Arofrez is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estroge... View More
What if you forget to take Arofrez?
If you miss a dose of Arofrez, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More
- You have been prescribed Arofrez for the treatment of breast cancer or infertility due to anovulation.
- It can be taken with or without food.
- Do not drive or do anything requiring concentration until you know how Arofrez affects you.
- It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
- Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Arofrez can alter their levels.
- Do not take Arofrez if you are pregnant or breastfeeding
Indication
Breast cancer
Administration
May be taken with or without food.
Adult Dose
Oral Advanced or locally advanced breast cancer ; Adjuvant therapy for postmenopausal women with hormone receptor positive early breast cancer Adult: ... View More
Contraindication
Premenopausal women and children; hypersensitivity.
Mode of Action
Letrozole competitively binds to the heme group of aromatase, a cytochrome P450 enzyme which catalyzes conversion of androgen to oestrogen, leading to i... View More
Precaution
Severe renal impairment; severe hepatic impairment; osteoporosis. Caution when driving or operating machinery. Lactation: not known if excreted in br... View More
Side Effect
Hot flushes, arthralgia, nausea, vomiting, fatigue, dizziness, headache, dyspepsia, constipation, diarrhoea, anorexia, alopoecia, increased sweating, ra... View More
Interaction
Plasma levels reduced by tamoxifen.
Alternative brand for Arofrez
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More