Introduction
Bufen SR is a pain relieving medicine. It is used to treat many conditions such as headache, fever, period pain, toothache, colds, and mild arthritis. I... View More
Uses of Bufen SR
Side effects of Bufen SR
How to use Bufen SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bufen SR is to be taken wi... View More
How Bufen SR works
Bufen SR is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and i... View More
Indication
Rheumatoid arthritis, Osteoarthritis, Pain, Fever, Pericarditis, Dysmenorrhea, Patent ductus arteriosus, Inflammation, Musculoskeletal and joint disorde... View More
Administration
Should be taken with food.
Adult Dose
Pain/Fever/Dysmenorrhea 200-400 mg PO q4-6hr; not to exceed 1.2 g unless directed by physician Inflammatory Disease 400-800 mg PO q6-8hr; not to ex... View More
Child Dose
Fever 6 months to 12 years 5-10 mg/kg/dose PO q6-8hr; not to exceed 40 mg/kg/day Pain 4-10 mg/kg/dose PO q6-8hr; not to exceed 40 mg/kg/day Ju... View More
Renal Dose
Significantly impaired renal function: Monitor closely; consider reduced dosage if warranted
Contraindication
Active peptic ulcer; hypersensitivity. Neonates with congenital heart disease, suspected necrotising enterocolitis and active bleeding (parenteral).
Mode of Action
Ibuprofen inhibits synthesis of prostaglandins in body tissues by inhibiting cyclooxygenase-1 and 2. It has anti-inflammatory, analgesic and antipyretic... View More
Precaution
Asthma; renal or hepatic disorders; bleeding disorders; CV disease. Pregnancy, lactation. Lactation: Drug excreted into breast milk; use not recommen... View More
Side Effect
1-10% Dizziness (3-9%),Epigastric pain (3-9%),Heartburn (3-9%),Constipation (1-3%),Nausea (3-9%),Rash (3-9%),Tinnitus (3-9%),Edema (1-3%),Fluid retenti... View More
Pregnancy Category Note
Pregnancy category: C; D in 3rd trimester or near delivery. At >30 weeks' gestation; may cause premature closure of ductus arteriosus
Interaction
Increased risk of GI bleeding w/ warfarin, corticosteroids, SSRIs and aspirin. May reduce the natriuretic effects of diuretics. Reduced antihypertensive... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More