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Beximco Pharmaceuticals Ltd.
Generic: Buprenorphine
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descriptionSafety Advices
It is unsafe to consume alcohol with Bugesic.
Bugesic may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing... View More
Bugesic is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Bugesic may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Bugesic should be used with caution in patients with severe kidney disease. Dose adjustment of Bugesic may be needed. Please consult your doctor.
Bugesic should be used with caution in patients with liver disease. Dose adjustment of Bugesic may be needed. Please consult your doctor. Use of Bugesic... View More
descriptionMedical Overview


Bugesic is used to treat moderate to severe pain and drug dependence/addiction to opioids. It helps to prevent withdrawal symptoms that may be caused du... View More

Uses of Bugesic

  • Opioid (Morphine) dependence

Side effects of Bugesic

  • Weakness
  • Drug withdrawal syndrome

How to use Bugesic

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bugesic may be taken with ... View More

How Bugesic works

Bugesic is a opioid partial agonist. It prevents withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drug... View More

quick tipsQuick Tips
  • Take it at the same time every day to help you remember to take it.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Use caution while driving or doing anything that requires concentration as Bugesic can cause dizziness and sleepiness.
  • Avoid drinking alcohol or taking other medicines that can cause drowsiness.
  • Discontinue the medicine and inform your doctor if you experience difficulty breathing.
  • Do not stop taking Bugesic without talking to your doctor first as it may cause a worsening of symptoms.
  • Your doctor may get regular blood tests to check for liver function while taking this medicine.
descriptionBrief Description


Pain, Anaesthesia, Opioid dependence


V Preparation Solution: Dilute to final concentration of 15 mcg/mL in D5W, D5/NS, NS, or LR Administer via controlled infusion device IV/IM Admin... View More

Adult Dose

Adult: Sublingual Moderate to severe pain 200-400 mcg 6-8 hrly. IV Perioperative analgesia 300-450 mcg via slow inj. IV/IM Moderate to severe pain... View More

Child Dose

Moderate-to-Severe Pain <2 years: Safety and efficacy not established 2-12 years: 2-6 mcg/kg slow IV/IM q4-6hr PRN >12 years: As in adults


Acute alcoholism; convulsive disorders; head injuries; increased intracranial pressure; comatose patients; resp depression and obstructive airway diseas... View More

Mode of Action

Buprenorphine exerts its analgesic effect by binding to the mu-opioid receptors in the CNS. It has a longer duration of analgesic action than morphine. ... View More


Hepatic or renal disease; pregnancy, lactation; hypothyroidism; adrenocortical insufficiency; asthma; prostatic hyperplasia; shock; hypotension; inflamm... View More

Side Effect

>10% Sedation (2/3 of patients) 1-10% Dizziness,Headache,Hypotension,Hypoventilation,Miosis,Nausea,Sweating,Vertigo,Vomiting <1% Abdominal cram... View More

Pregnancy Category Note

Pregnancy Data in pregnancy are limited; however, these data do not indicate an increased risk of major malformations specifically due to buprenorphine... View More


Plasma-buprenorphine concentrations may be affected when co-administered with drugs that induce or inhibit cytochrome P450 isoenzyme CYP3A4. Enhanced de... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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