Hypertension, Heart failure, Oedema, Nephrotic syndrome
May be taken with or without food. May be taken w/ meals to reduce GI discomfort.
Oral Oedema Adult: 1 mg once daily. Give 2nd dose 6-8 hr later if necessary. Elderly: 0.5 mg daily. Refractory oedema Adult: Initially, 5 mg dail... View More
Hypersensitivity, progressive renal failure and anuria, hepatic coma, severe electrolyte depletion.
Mode of Action
Bumetanide induces diuresis by inhibiting reabsorption of water and electrolytes (sodium and chloride) in the ascending loop of Henle and proximal renal... View More
Pregnancy, lactation; regular monitoring of serum electrolytes (especially potassium, calcium, magnesium); in case of hypokalemia, potassium supplements... View More
>10% Hyperuricemia (18%),Hypochloremia (15%),Hypokalemia (15%),Azotemia (11%) 1-10% Hyponatremia (9%),Hyperglycemia (7%),Increased serum creatinine... View More
Pregnancy Category Note
Pregnancy category: C Lactation: Unknown whether drug is excreted in breast milk; use with caution
Reduced diuretic and natriuretic actions by probenecid. Indometacin blunts action of bumetanide; concurrent usage with antihypertensives may increase ri... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More