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Calm 10
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Calm 1010mg

Tablet
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Biopharma Ltd.
Generic: Clobazam
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2.48
MRP
2.76
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
Calm 10 may cause excessive drowsiness with alcohol.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Calm 10 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Calm 10 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Short-... View More
DrivingDriving
UNSAFE
Calm 10 may cause side effects which could affect your ability to drive. You may feel sleepy or have concentration or memory problems after taking Calm ... View More
KidneyKidney
CAUTION
Calm 10 should be used with caution in patients with kidney disease. Dose adjustment of Calm 10 may be needed. Please consult your doctor. Limited infor... View More
LiverLiver
CAUTION
Calm 10 should be used with caution in patients with liver disease. Dose adjustment of Calm 10 may be needed. Please consult your doctor. Limited inform... View More
descriptionMedical Overview

Introduction

Calm 10 belongs to a class of medicines known as benzodiazepines. It is a prescription medicine used to treat epilepsy (seizures) and severe anxiety. It... View More

Uses of Calm 10

  • Severe anxiety
  • Epilepsy/Seizures

Side effects of Calm 10

Common
  • Aggressive behavior
  • Breathing problems
  • Constipation
  • Cough
  • Difficulty in urination
  • Drooling
  • Fever
  • Insomnia (difficulty in sleeping)
  • Sleepiness
  • Slurred speech
  • Tiredness

How to use Calm 10

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Calm 10 may be taken with ... View More

How Calm 10 works

Calm 10 is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of th... View More

quick tipsQuick Tips
  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Inform your doctor if you notice sores or blisters on your skin, lips, or inside your mouth.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremo... View More
descriptionBrief Description

Indication

Anxiety, tension, irritability, restlessness, epilepsy.

Administration

May be taken with or without food. Individualize weight-based dose according to clinical efficacy and tolerability Doses above 5 mg/day should be ... View More

Adult Dose

Seizures Indicated for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in patients aged 2 years or older >30 kg: In... View More

Child Dose

Seizures Indicated for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in patients aged 2 years or older <30 kg St... View More

Renal Dose

Renal impairment Mild or moderate renal impairment: No dose adjustment required Severe renal impairment or ESRD: No experience

Contraindication

Hypersensitivity; history of drug dependence; myasthaenia gravis; pregnancy (1st trimester), lactation; serious liver damage; sleep apnoea syndrome; imp... View More

Mode of Action

Clobazam binds to one or more specific GABA receptors at several sites within the CNS including the limbic system and reticular formation. Increased per... View More

Precaution

May impair ability to perform skilled tasks and hazardous activities; elderly; renal or hepatic impairment; alcoholics; obesity; withdrawal should be gr... View More

Side Effect

>10% Somnolence or sedation (26%),Somnolence (22%),Pyrexia (13%),Upper respiratory tract infection (12%) 1-10% Drooling (9%),Aggression (8%),Irrita... View More

Pregnancy Category Note

Pregnancy There are no adequate and well-controlled studies in pregnant women; available data suggest that the class of benzodiazepines is not associat... View More

Interaction

Increased hepatic clearance of clobazam when administered with phenytoin, phenobarbital or carbamazepine. Cimetidine may increase levels of clobazam. ... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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