Introduction
Canazole 50 belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat infections of the mouth, ... View More
Uses of Canazole 50
Side effects of Canazole 50
How to use Canazole 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Canazole 50 may be taken w... View More
How Canazole 50 works
Canazole 50 is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infectio... View More
What if you forget to take Canazole 50?
If you miss a dose of Canazole 50, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
Indication
Cryptococcal meningitis, Candidiasis, Tinea pedis, Tinea cruris, Tinea corporis, Vaginal candidiasis, Onychomycosis, Coccidioidomycosis, Cryptococcosis,... View More
Administration
May be taken with or without food Reconstitution: Powd for oral susp: Add 24 mL of distilled or purified water to the container labeled as containing... View More
Adult Dose
Oral Oropharyngeal Candidiasis 200 mg PO on Day 1, THEN 100 mg qDay Treatment should be continued for at least 2 weeks to decrease likelihood of rela... View More
Child Dose
Child: PO 3–12 mg/kg/day, max 600 mg/day q24h Max 800–1,000 mg/day may be used for some CNS fungal infections Age Average Weight Dose/Day ... View More
Renal Dose
Renal impairment: Haemodialysis patients: Usual dose given after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis 50% ... View More
Contraindication
Hypersensitivity.
Mode of Action
Fluconazole decreases ergosterol synthesis by interfering w/ cytochrome P450 activity, thus inhibiting cell membrane formation of susceptible fungi incl... View More
Precaution
Renal or hepatic impairment. May prolong QT interval. Pregnancy, lactation. CDC guidelines recommend only using topical antifungal products to treat pre... View More
Side Effect
>10% Headache (2-13%) 1-10% Nausea (2-7%),Abdominal pain (2-6%),Diarrhea (2-3%),Rash (2%),Vomiting (2-5%) Frequency Not Defined QT prolongation... View More
Pregnancy Category Note
Pregnancy Single maternal PO dose of 150 mg for vaginal candidiasis Results of a Danish study concludes there is a possible increased risk of miscarri... View More
Interaction
May increase plasma concentrations of oral hypoglycaemics (e.g. tolbutamide, glyburide, glipizide), phenytoin, theophylline, tofacitinib, rifabutin. May... View More
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More