Introduction
Capcitab is used in the treatment of cancer of breast, colon, and rectum. It may be also used to treat other conditions, as determined by the doctor. It... View More
Uses of Capcitab
Side effects of Capcitab
How to use Capcitab
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Capcitab is to be taken wi... View More
How Capcitab works
Capcitab is an anticancer medication. Inside the body, this medicine gets converted into 5-fluorouracil (chemical). This chemical hampers the synthesis ... View More
Indication
Breast cancer, Colorectal cancer, Gastric cancer, Oesophageal cancer
Administration
Swallow with water within 30 min after a meal
Adult Dose
Oral Breast cancer; Colorectal cancer Adult: 1.25 g/m2 bid for 2 wk followed by a 1 wk rest period; therapy to be given in 3-wk cycles. Recommended tr... View More
Renal Dose
Renal impairment: CrCl (ml/min) 51-80 No adjustment needed. 30-50 Reduce dose to 950 mg/m2 bid when starting dose is 1.25 g/m2 bid. No dose adjustme... View More
Contraindication
History of severe and unexpected reactions to fluoropyrimidine therapy; severe renal impairment; pregnancy, lactation. Hypersensitivity.
Mode of Action
Capecitabine is a prodrug that is converted to fluorouracil following oral administration, which in turn inhibits thymidylate synthetase, blocking the m... View More
Precaution
Hepatic dysfunction, bone marrow suppression, poor nutritional status, warfarin therapy. Child, elderly, prior extensive pelvic radiation or alkylating ... View More
Side Effect
10% Diarrhea,Nausea,Anemia,Lymphopenia,Hand and foot syndrome,Edema,Fatigue,Fever,Headache,Pain,Paresthesia,Alopecia,Dermatitis,Abdominal pain,Anorexia... View More
Pregnancy Category Note
Pregnancy Category: C Lactation: excretion in milk unknown; use with caution
Interaction
Antacids containing aluminum and magnesium, leucovorin, anticoagulants, phenytoin, allopurinol.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More