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Capcitab500mg
Tablet
Require PrescriptionEskayef Pharmaceuticals Ltd.
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LiverMedical OverviewIntroduction
Capcitab is used in the treatment of cancer of breast, colon, and rectum. It may be also used to treat other conditions, as determined by the doctor. It... View More
Uses of Capcitab
- Breast cancer
- Cancer of colon and rectum
Side effects of Capcitab
- Vomiting
- Weakness
- Nausea
- Abdominal pain
- Diarrhea
- Blisters on fingers/feet
How to use Capcitab
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Capcitab is to be taken wi... View More
How Capcitab works
Capcitab is an anticancer medication. Inside the body, this medicine gets converted into 5-fluorouracil (chemical). This chemical hampers the synthesis ... View More
Quick Tips- Capcitab is used alone or in combination with other medicines for the treatment of colon, rectum or breast cancers.
- It is oral chemotherapy, hence it is preferred by many patients.
- It should be taken within 30 minutes after eating a meal.
- The dose and the number of treatment cycles needed will depend on the type and stage of cancer that is being treated.
- It may cause dizziness and tiredness. Don't drive or do anything requiring concentration until you know how it affects you.
- Frequency of hair loss is much less compared to other chemotherapy drugs.
- Do not take it if you are pregnant or breastfeeding.
- Your doctor may regularly monitor your blood cells during treatment with this medicine. Inform your doctor immediately if you notice signs of infection ... View More
- Inform your doctor immediately if you start to have side effects such as diarrhea, vomiting, nausea, mouth sores, chest pain or loss of appetite.
Brief DescriptionIndication
Breast cancer, Colorectal cancer, Gastric cancer, Oesophageal cancer
Administration
Swallow with water within 30 min after a meal
Adult Dose
Oral Breast cancer; Colorectal cancer Adult: 1.25 g/m2 bid for 2 wk followed by a 1 wk rest period; therapy to be given in 3-wk cycles. Recommended tr... View More
Renal Dose
Renal impairment: CrCl (ml/min) 51-80 No adjustment needed. 30-50 Reduce dose to 950 mg/m2 bid when starting dose is 1.25 g/m2 bid. No dose adjustme... View More
Contraindication
History of severe and unexpected reactions to fluoropyrimidine therapy; severe renal impairment; pregnancy, lactation. Hypersensitivity.
Mode of Action
Capecitabine is a prodrug that is converted to fluorouracil following oral administration, which in turn inhibits thymidylate synthetase, blocking the m... View More
Precaution
Hepatic dysfunction, bone marrow suppression, poor nutritional status, warfarin therapy. Child, elderly, prior extensive pelvic radiation or alkylating ... View More
Side Effect
10% Diarrhea,Nausea,Anemia,Lymphopenia,Hand and foot syndrome,Edema,Fatigue,Fever,Headache,Pain,Paresthesia,Alopecia,Dermatitis,Abdominal pain,Anorexia... View More
Pregnancy Category Note
Pregnancy Category: C Lactation: excretion in milk unknown; use with caution
Interaction
Antacids containing aluminum and magnesium, leucovorin, anticoagulants, phenytoin, allopurinol.
Alternative brand for Capcitab
DisclaimerThe information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More
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