Capsi

Indication

Rheumatoid arthritis, Osteoarthritis, Psoriasis, Post-herpetic neuralgia, Anogenital pruritus, Sprains, Stiff neck, Low back pain, Trigeminal neuralgia,... View More

Administration

Apply a thin film of Capsaicin cream to affected area. A burning sensation may occur upon application, but generally disappears with regular use. Wash h... View More

Adult Dose

Apply to affected area three/four times daily for 3-4 consecutive weeks and evaluate efficacy; efficacy decreased if used < 3 times daily; not to exceed... View More

Child Dose

Safety & efficacy not established

Contraindication

Capsaicin cream is contraindicated for use on broken or irritated skin or known hypersensitivity to this medication.

Mode of Action

Transient receptor potential vanilloid-1 (TRPV1) agonist; topical application causes initial TRPV1 stimulation that may cause pain, followed by pain rel... View More

Precaution

Capsaicin cream should not be applied to broken or irritated skin. Applied area should not be tightly bandaged. Do not get on mucous membranes and into ... View More

Side Effect

>10% Transient increased pain at application site (dissipates w/ continued use),Application site erythema (63%),Pain (42%) 1-10% Nausea (5%),Vomiti... View More

Pregnancy Category Note

Pregnancy Category: B Lactation: Unknown whether distributed in breast milk; do not apply to nipple or areola

Interaction

Capsaicin, including topical use, may cause or exacerbate coughing associated with ACE inhibitor treatment and vice versa. If a severe cough develops in... View More