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Carbestop
Incepta Pharmaceuticals Ltd.
Generic: Carboprost
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Carbestop. Please consult your doctor.
UNSAFE
Carbestop is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
CAUTION
Carbestop should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
UNSAFE
Carbestop may cause side effects which could affect your ability to drive.
As Carbestop may make you lose consciousness, feel dizzy or drowsy and this may affect your ability to drive
CAUTION
Carbestop should be used with caution in patients with kidney disease. Dose adjustment of Carbestop may be needed. Please consult your doctor.
Use of Carbestop is not recommended in patients with active kidney disease.
CAUTION
Carbestop should be used with caution in patients with liver disease. Dose adjustment of Carbestop may be needed. Please consult your doctor.
Use of Carbestop is not recommended in patients with active liver disease.
Medicine Overview of Carbestop 250mcg/ml Injection
Introduction
Carbestop is a medicine used to control excessive bleeding from the uterus, that may occur after the childbirth. It stimulates contraction of the uterine muscles thus, helps to control post-delivery bleeding. Carbestop is given as an injection deep into the muscles under the medical supervision of a doctor. It is only given at the hospital sitting, so do not self- administered the medicine. The dose and how often you take it depends on what you are taking it for. You should take this medicine for as long as it is prescribed for you. The most common side effects of this...
... Show moreUses of Carbestop
- Post-delivery bleeding
Side effects of Carbestop
Common
- Vomiting
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Headache
- Nausea
- Chills
- Diarrhea
- Placental retention
- Cough
How to use Carbestop
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Carbestop works
Carbestop stimulates contraction of the uterine muscles, helping to control post-delivery bleeding.
Quick Tips
- Carbestop increases the contraction of your womb which helps to control excessive bleeding after delivery.
- It is injected deep in to a muscle by your doctor or nurse.
- It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
- It may cause an increase in body temperature. This will return to normal few hours after the last injection.
- Inform your doctor if you have problems with your heart, lung, kidney or liver.
Brief Description
Indication
Pregnancy termination in the 2nd trimester (Abortion), Postpartum Uterine Bleeding
Adult Dose
Intramuscular
Pregnancy termination in the 2nd trimester/Abortion
Adult: Initially, 250 mcg. Alternatively, initiate w/ test dose of 100 mcg. May be repeated at 1.5- to 3.5-hr intervals depending on uterine response. May be increased to 500 mcg if uterine contractility is inadequate.
Max: 12 mg. Max duration: 2 days.
Intramuscular
Postpartum haemorrhage
Adult: Initially, 250 mcg by deep inj. May be repeated every 15-90-min. Max: 2 mg.
Contraindication
Acute pelvic inflammatory disease; active cardiac, pulmonary, renal or hepatic disease.
Mode of Action
Carboprost, a synthetic analogue of naturally occurring prostaglandin F2α, stimulates uterine contractility, resulting in expulsion of the products of conception. It is also used to induce abortion between 13-20 wk of pregnancy. It produces myometrial contractions responsible for placental haemostasis.
Precaution
History of glaucoma or raised IOP
Asthma, hypertension/hypotension, cardiovascular disease
Transient fever observed with treatment possibly as a result of carboprost's effect on hypothalamic thermoregulation
Caution in patients with anemia, jaundice, renal impairment, hepatic impairment diabetes or epilepsy
To decrease GI side effects pretreatment or concomitant use with antiemetic and antidiarrheal agents recommended
Not for IV
Rare cases of cardiovascular collapse reported with prostaglandins
Lactation: Excretion in milk unknown
Side Effect
Nausea (1/3 patients), Vomiting (~2/3 patients),Diarrhea (~2/3 patients)
Nervousness,Epistaxis,Sleep disorder,Hyperthermia,Flushing,Asthma,Wheezing,Coughing,Chest pain,Hypertension,Syncope,Palpation,Tachycardia,Chest tightness,Anxiety,Chills/shivering,Dizziness,Drowsiness,Dystonia,Faintness,Headache,Lethargy,Lightheadedness,Vertigo,Rash,Breast tenderness,Dysmenorrhea-like pain,Hot flashes,Dry throat.Taste alterations,Uterine bleeding (excessive)
Local: injection site pain
Backache,Leg cramps,Muscular pain,Parethesia,Blurred vision,Eye pain,Eyelid twitching,Tinnitus,Bronchospasm,Dyspnea,Hiccups
Pregnancy Category Note
Pregnancy Category: C
Lactation: Excretion in milk unknown
Interaction
May potentiate effect of other oxytocics.
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