Carbotor150mg

Introduction

Carbotor is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer ce... View More

Uses of Carbotor

• Ovarian cancer
• Small cell lung cancer

Side effects of Carbotor

• Nausea
• Vomiting
• Anemia (low number of red blood cells)
• Fatigue
• Low blood platelets
• Increased liver enzymes
• Decreased white blood cell count (neutrophils)
• Stomatitis (Inflammation of the mouth)
• Peripheral neuropathy (tingling and numbness of feet and hand)
• Diarrhea

How to use Carbotor

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Carbotor works

Carbotor is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multipli... View More

What if you forget to take Carbotor?

If you miss a dose of Carbotor, please consult your doctor.

Indication

Ovarian carcinoma, Lung cancer

Administration

IV Preparation Single-dose lyophilized powder (reconstitution require) Reconstitute powder with sterile water for injection, D5W, or 0.9% NaCl to yiel... View More

Adult Dose

Intravenous Small cell lung cancer; Advanced ovarian carcinoma Adult: IV As single agent in treatment-naive patients: 400 mg/m2; As single agent in ... View More

Child Dose

Solid tumor 300-600 mg/m² IV q4Weeks Sarcoma (bone/soft tissue) 400 mg/m²/day for 2 days every 21 days Brain tumor 175 mg/m² qWeek x 4 weeks w... View More

Renal Dose

Renal impairment: CrCl (ml/min) >40 Recommended dose: 400 mg/m2. 20-39 Recommended dose: 250 mg/m2.

Contraindication

Previous allergy; pregnancy, lactation; allergy to other platinum compounds; severe bone marrow depression; significant bleeding, aluminium containing n... View More

Mode of Action

Carboplatin is an alkylating agent which binds covalently to DNA. It modifies the cell cycle by interfering with DNA structure and function.

Precaution

Neonates; diminished renal function; neurotoxicity; liver function impairment. Lactation: not known if excreted in breast milk; do not nurse

Side Effect

>10% Leukopenia (26-97%),Neutropenia (21-96%),Nausea (81-93%),Vomiting (81-93%),Anemia (14-90%),Magnesium loss (43-61%),Thrombocytopenia (33-66%),Alope... View More

Pregnancy Category Note

Pregnancy Category: D Lactation: not known if excreted in breast milk; do not nurse

Interaction

Increased risk of ototoxicity when used with aminoglycosides.