Livacol 55mg
Tablet
Square Pharmaceuticals PLC.
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Indication
Primary Biliary Cholangitis Indicated for primary biliary cholangitis (PBC), in combination with ursodeoxycholic acid (UDCA) in adults with an inadequa... View More
Administration
May take with or without food Concomitant bile-acid binding resin: Separate obeticholic acid dose by at least 4 hr
Adult Dose
Adult Tablet Primary Biliary Cholangitis Indicated for primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults wi... View More
Contraindication
Complete biliary obstruction
Mode of Action
Farnesoid X receptor (FXR) agonist FXR is a nuclear receptor expressed in the liver, intestine, kidney, and adipose tissue that regulates a wide vari... View More
Precaution
Hepatic decompensation and failure, in some cases fatal, reported in patients with PBC who have decompensated cirrhosis or Child-Pugh Class B or C hepat... View More
Side Effect
>10% Pruritus (56-70%) Fatigue (19-25%) Severe pruritus (19-23%) Reduced HDL-C (9-20%) Abdominal pain and discomfort (10-19%) 1-10% Rash (7-10%... View More
Interaction
Bile-acid binding resins may reduce the absorption, systemic exposure, and efficacy of obeticholic acid Coadministration of warfarin and obeticholic ac... View More
Alternative brand for Livacol 5
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More