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Carplatin 450450mg/45ml

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Drug International Ltd.
Generic: Carboplatin
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descriptionSafety Advices
It is not known whether it is safe to consume alcohol with Carplatin 450. Please consult your doctor.
Carplatin 450 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe i... View More
Carplatin 450 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Carplatin 450 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Carplatin 450 should be used with caution in patients with kidney disease. Dose adjustment of Carplatin 450 may be needed. Please consult your doctor. U... View More
Carplatin 450 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Carplatin 450 may not be n... View More
descriptionMedical Overview


Carplatin 450 is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of canc... View More

Uses of Carplatin 450

  • Ovarian cancer
  • Small cell lung cancer

Side effects of Carplatin 450

  • Nausea
  • Vomiting
  • Anemia (low number of red blood cells)
  • Fatigue
  • Low blood platelets
  • Increased liver enzymes
  • Decreased white blood cell count (neutrophils)
  • Stomatitis (Inflammation of the mouth)
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Diarrhea

How to use Carplatin 450

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Carplatin 450 works

Carplatin 450 is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and mul... View More

What if you forget to take Carplatin 450?

If you miss a dose of Carplatin 450, please consult your doctor.

quick tipsQuick Tips
  • It is given as an injection into the veins under the supervision of a doctor.
descriptionBrief Description


Ovarian carcinoma, Lung cancer


IV Preparation Single-dose lyophilized powder (reconstitution require) Reconstitute powder with sterile water for injection, D5W, or 0.9% NaCl to yiel... View More

Adult Dose

Intravenous Small cell lung cancer; Advanced ovarian carcinoma Adult: IV As single agent in treatment-naive patients: 400 mg/m2; As single agent in ... View More

Child Dose

Solid tumor 300-600 mg/m² IV q4Weeks Sarcoma (bone/soft tissue) 400 mg/m²/day for 2 days every 21 days Brain tumor 175 mg/m² qWeek x 4 weeks w... View More

Renal Dose

Renal impairment: CrCl (ml/min) >40 Recommended dose: 400 mg/m2. 20-39 Recommended dose: 250 mg/m2.


Previous allergy; pregnancy, lactation; allergy to other platinum compounds; severe bone marrow depression; significant bleeding, aluminium containing n... View More

Mode of Action

Carboplatin is an alkylating agent which binds covalently to DNA. It modifies the cell cycle by interfering with DNA structure and function.


Neonates; diminished renal function; neurotoxicity; liver function impairment. Lactation: not known if excreted in breast milk; do not nurse

Side Effect

>10% Leukopenia (26-97%),Neutropenia (21-96%),Nausea (81-93%),Vomiting (81-93%),Anemia (14-90%),Magnesium loss (43-61%),Thrombocytopenia (33-66%),Alope... View More

Pregnancy Category Note

Pregnancy Category: D Lactation: not known if excreted in breast milk; do not nurse


Increased risk of ototoxicity when used with aminoglycosides.

Alternative brand for Carplatin 450
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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