Apixan 55mg
Tablet
Unimed Unihealth Pharmaceuticals Ltd.
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| Alcohol | CAUTION Caution is advised when consuming alcohol with Apixan 5. Please consult your doctor. |
| Pregnancy | SAFE IF PRESCRIBED Apixan 5 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, ther... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Apixan 5 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | SAFE Apixan 5 does not usually affect your ability to drive. |
| Kidney | CAUTION Apixan 5 should be used with caution in patients with kidney disease. Dose adjustment of Apixan 5 may be needed. Please consult your doctor. |
| Liver | CAUTION Apixan 5 should be used with caution in patients with liver disease. Dose adjustment of Apixan 5 may be needed. Please consult your doctor.
Dose adjustm... View More |
Introduction
Apixan 5 is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and h... View More
Uses of Apixan 5
- Deep vein thrombosis
- Pulmonary embolism
- Stroke prevention
How to use Apixan 5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apixan 5 may be taken with... View More
How Apixan 5 works
Apixan 5 is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.
What if you forget to take Apixan 5?
If you miss a dose of Apixan 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More
- For best results, take Apixan 5 at the same time every day. It is better to take at night with meals
- It interacts less with food or other medicines. Hence, frequent dose changes are not required.
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. f... View More
- Inform your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
- If you are going to have a surgery or dental treatment, you may be asked to stop taking Apixan 5 temporarily.
- Notify your doctor if you have any kidney problem.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- Do not stop taking medication without talking to your doctor.
Indication
Indicated to reduce risk of stroke and systemic embolism associated with nonvalvular atrial fibrillation, Postoperative Prophylaxis of DVT/PE following ... View More
Administration
May be taken with or without food.
Adult Dose
Oral Adult Prevention of VTE: Elective hip or knee replacement surgery Tablet 2.5 mg twice daily. Initial dose should be taken 12-24 hr post-op. Re... View More
Renal Dose
Renal impairment, including with ESRD on dialysis Deep Vein Thrombosis: No dose adjustment recommended; clinical efficacy and safety studies did not en... View More
Contraindication
Hypersensitivity. Clinically significant active bleeding. Hepatic disease associated w/ coagulopathy & clinically relevant bleeding risk. Lesion or cond... View More
Mode of Action
Apixaban is an anticoagulant that inhibits platelet activation and fibrin clot formation via direct, selective and reversible inhibition of free and clo... View More
Precaution
Increased risk of hemorrhage eg, congenital or acquired bleeding disorders; active ulcerative GI disease; bacterial endocarditis; thrombocytopenia; plat... View More
Side Effect
Epistaxis, haematoma, anaemia, haematuria, contusion, nausea; GI, rectal or gingival haemorrhage. Potentially Fatal: Epidural or spinal haematoma, fata... View More
Pregnancy Category Note
Pregnancy There are no adequate and well-controlled studies in pregnant women Treatment is likely to increase the risk of hemorrhage during pregnanc... View More
Interaction
Increased exposure w/ strong dual CYP3A4 and P-glycoprotein (P-gp) inhibitors (e.g. clarithromycin, itraconazole, ketoconazole, ritonavir). Increased ri... View More
Alternative brand for Apixan 5
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More