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Tofacent 1010mg

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Incepta Pharmaceuticals Ltd.
Generic: Tofacitinib
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descriptionSafety Advices
Consuming alcohol with Tofacent 10 does not cause any harmful side effects.
Tofacent 10 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More
Tofacent 10 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Tofacent 10 does not usually affect your ability to drive.
There is no data available. Please consult doctor before consuming the drug.
There is no data available. Please consult doctor before consuming the drug.
descriptionMedical Overview


Tofacent 10 is used to treat moderate to severe rheumatoid arthritis. It helps decrease pain, tenderness and swelling in the joints by reducing inflamma... View More

Uses of Tofacent 10

  • Rheumatoid arthritis

Side effects of Tofacent 10

  • Diarrhea
  • Headache
  • High blood pressure
  • Nasal congestion (stuffy nose)
  • Runny nose
  • Sore throat
  • Upper respiratory tract infection

How to use Tofacent 10

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tofacent 10 may be taken w... View More

How Tofacent 10 works

Tofacent 10 is an Janus kinase inhibitor. It works by blocking the action of the enzyme, Janus kinase. This decreases inflammation and joint damage in r... View More

quick tipsQuick Tips
  • Tofacent 10 is used alone or in combination with other medicines for the treatment of rheumatoid arthritis, that did not improve with other anti-rheumat... View More
  • It may take take 3 to 6 months to feel the maximum effect of this medication. Keep taking it as prescribed.
  • Your doctor may get regular blood tests done to monitor your liver function, kidney function, blood counts, or cholesterol levels.
  • Tofacent 10 can make it a bit harder for people to fight off infections. Inform your doctor if you have symptoms of an infection such as fever, chills, ... View More
  • Your doctor may get TB (tuberculosis) skin test and a chest X-ray before starting treatment with this medication.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
descriptionBrief Description


Rheumatoid Arthritis, Tofacitinib is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis who have had... View More


May be taken with or without food.

Adult Dose

Rheumatoid Arthritis Indicated as second-line treatment for moderate-to-severe active rheumatoid arthritis in patients with an inadequate response or i... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment Mild: No dosage adjustment required Moderate-to-severe: Not to exceed 5 mg qDay


Hypersensitivity to the active substance or to any of the excipients.

Mode of Action

Janus kinases (JAKs) pathways inhibitor; JAK consists of a group of intracellular tyrosine kinases that transmit signals from cytokine or growth factor-... View More


Serious Infections – Do not administer Tofacitinib during an active infection, including localized infections. If a serious infection develops, interrup... View More

Side Effect

>10% Overall infections (20-22%) 1-10% URTI (4.5%),Headache (4.3%),Diarrhea (4%),Nasopharyngitis (3.8%),UTI (2%),Hypertension (1.6%) <1% ANC <5... View More

Pregnancy Category Note

Pregnancy There is a pregnancy exposure registry that monitors pregnancy outcomes in women during pregnancy; patients can call the toll free number 1-8... View More


Increased exposure w/ potent CYP3A4 inhibitors (eg, ketoconazole), moderate CYP3A4 inhibitors & potent CYP2C19 inhibitors (eg, fluconazole). Decreased e... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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