Tofacent 1010mg
Tablet
Incepta Pharmaceuticals Ltd.
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| Alcohol | SAFE Consuming alcohol with Tofacent 10 does not cause any harmful side effects. |
| Pregnancy | CONSULT YOUR DOCTOR Tofacent 10 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Tofacent 10 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | SAFE Tofacent 10 does not usually affect your ability to drive. |
| Kidney | There is no data available. Please consult doctor before consuming the drug. |
| Liver | There is no data available. Please consult doctor before consuming the drug. |
Introduction
Tofacent 10 is used to treat moderate to severe rheumatoid arthritis. It helps decrease pain, tenderness and swelling in the joints by reducing inflamma... View More
Uses of Tofacent 10
- Rheumatoid arthritis
Side effects of Tofacent 10
- Diarrhea
- Headache
- High blood pressure
- Nasal congestion (stuffy nose)
- Runny nose
- Sore throat
- Upper respiratory tract infection
How to use Tofacent 10
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tofacent 10 may be taken w... View More
How Tofacent 10 works
Tofacent 10 is an Janus kinase inhibitor. It works by blocking the action of the enzyme, Janus kinase. This decreases inflammation and joint damage in r... View More
- Tofacent 10 is used alone or in combination with other medicines for the treatment of rheumatoid arthritis, that did not improve with other anti-rheumat... View More
- It may take take 3 to 6 months to feel the maximum effect of this medication. Keep taking it as prescribed.
- Your doctor may get regular blood tests done to monitor your liver function, kidney function, blood counts, or cholesterol levels.
- Tofacent 10 can make it a bit harder for people to fight off infections. Inform your doctor if you have symptoms of an infection such as fever, chills, ... View More
- Your doctor may get TB (tuberculosis) skin test and a chest X-ray before starting treatment with this medication.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Indication
Rheumatoid Arthritis, Tofacitinib is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis who have had... View More
Administration
May be taken with or without food.
Adult Dose
Rheumatoid Arthritis Indicated as second-line treatment for moderate-to-severe active rheumatoid arthritis in patients with an inadequate response or i... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment Mild: No dosage adjustment required Moderate-to-severe: Not to exceed 5 mg qDay
Contraindication
Hypersensitivity to the active substance or to any of the excipients.
Mode of Action
Janus kinases (JAKs) pathways inhibitor; JAK consists of a group of intracellular tyrosine kinases that transmit signals from cytokine or growth factor-... View More
Precaution
Serious Infections – Do not administer Tofacitinib during an active infection, including localized infections. If a serious infection develops, interrup... View More
Side Effect
>10% Overall infections (20-22%) 1-10% URTI (4.5%),Headache (4.3%),Diarrhea (4%),Nasopharyngitis (3.8%),UTI (2%),Hypertension (1.6%) <1% ANC <5... View More
Pregnancy Category Note
Pregnancy There is a pregnancy exposure registry that monitors pregnancy outcomes in women during pregnancy; patients can call the toll free number 1-8... View More
Interaction
Increased exposure w/ potent CYP3A4 inhibitors (eg, ketoconazole), moderate CYP3A4 inhibitors & potent CYP2C19 inhibitors (eg, fluconazole). Decreased e... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More