Introduction
Cellcept belongs to a group of medicines called immunosuppressants. It is used with other medicines to prevent your body from rejecting an organ (such a... View More
Uses of Cellcept
Side effects of Cellcept
How to use Cellcept
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cellcept may be taken with... View More
How Cellcept works
Cellcept is an immunosuppressant. It reduces the action of body's own defence system (the immune system) and prevents rejection of the transplanted orga... View More
Indication
Prophylaxis of acute renal graft rejection, Prophylaxis of cardiac graft rejection, Liver Transplant
Administration
Drug is taken on empty stomach 1 hour before or 2 hours after meals Once dosage is stabilized, MMF can be taken with food after kidney transplant
Adult Dose
Oral Adult Prophylaxis of acute renal graft rejection As Mycophenolate Mofetil (MMF): 1 g twice daily starting w/in 72 hr of transplantation. Max: 2 ... View More
Child Dose
<3 months Safety and efficacy not established >3 months Prophylaxis of organ rejection in patients receiving allogeneic renal transplants As Mycop... View More
Renal Dose
Renal impairment MMF: In severe renal impairment (glomerular filtration rate [GFR] <25 mL/min/1.73 m²), not to exceed 1 g q12hr No dosage adjustment n... View More
Contraindication
Pregnancy, lactation. Rare hereditary deficiency of hypoxanthine-guanine phosphoribosyltransferase (HGPRT), including Kelley-Seegmiller or Lesch-Nyhan s... View More
Mode of Action
Mycophenolic acid acts by blocking purine synthesis of human lymphocytes through reversible inhibition of inosine monophosphate dehydrogenase. It also i... View More
Precaution
Teratogenic in animals; avoid inhalation or direct skin contact. Monitor patients for lymphoproliferative disorders; advise patient to limit exposure to... View More
Side Effect
>10% Hyperglycemia (44%),Hypercholesterolemia (41%),Hypomagnesemia (39%),Dyspnea (37%),Back pain (35%),Increased blood urea nitrogen (BUN) (35%),Leukop... View More
Interaction
Increased plasma levels of both drugs when combined with aciclovir, valaciclovir, ganciclovir and valganciclovir. Reduced absorption with colestyramine,... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More