Introduction
Centoxin is a medicine used for the treatment of heart failure in combination with other medicines. It helps to provide symptomatic relief by making the... View More
Uses of Centoxin
Side effects of Centoxin
How to use Centoxin
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Centoxin may be taken with... View More
How Centoxin works
Centoxin is a cardiac glycoside. It works by correcting irregular heartbeat to a normal rhythm and increases the force with which the heart muscle contr... View More
What if you forget to take Centoxin?
If you miss a dose of Centoxin, skip it and continue with your normal schedule. Do not double the dose.
Indication
Heart failure, Supraventricular arrhythmias, Atrial fibrillation and Atrial flutter
Administration
May be taken with or without food.
Adult Dose
Atrial Fibrillation Rapid digitalizing (loading-dose) regimen PO: 10-15 mcg/kg total loading dose; administer 50% initially; then may cautiously give ... View More
Child Dose
Heart Failure/Atrial Fibrillation Use doses at the lower end of the spectrm when treating heart failure Reduce dose by 20-25% when changing from oral ... View More
Renal Dose
Use lower end of dosing (0.125 mg/day) in patients with impaired renal function
Contraindication
Digitalis toxicity, ventricular tachycardia/fibrillation, obstructive cardiomyopathy. Arrhythmias due to accessory pathways (e.g. Wolff-Parkinson-White ... View More
Mode of Action
Digoxin is a cardiac glycoside which has positive inotropic activity characterized by an increase in the force of myocardial contraction. It also reduce... View More
Precaution
Cardiac dysrhythmias, hypokalaemia, hypertension, IHD, hypercalcaemia, hypomagnesaemia, electroconversion, chronic cor pulmonale, aortic valve disease, ... View More
Side Effect
1-10% Dizziness (4.9%),Mental disturbances (4.1%),Diarrhea (3.2%),Headache (3.2%),Nausea (3.2%),Vomiting (1.6%),Maculopapular rash (1.6%) <1% Anore... View More
Pregnancy Category Note
Pregnancy Experience with digoxin in pregnant women over several decades, based on published retrospective clinical studies and case reports, has not l... View More
Interaction
Effectiveness reduced by phenytoin, neomycin, sulphasalazine, kaolin, pectin, antacids and in patients receiving radiotherapy. Metoclopramide may alter ... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More