Introduction
Centradol 50 is a medicine used to treat moderate to severe acute pain in adults. It is used to treat many conditions such as headache, fever, period pa... View More
Uses of Centradol 50
Side effects of Centradol 50
How to use Centradol 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Centradol 50 may be taken ... View More
How Centradol 50 works
Centradol 50 decreases the perception of pain by blocking the transmission of pain signals to the brain.
What if you forget to take Centradol 50?
If you miss a dose of Centradol 50, skip it and continue with your normal schedule. Do not double the dose.
Indication
Acute Moderate-to-Severe Pain, Musculoskeletal pain, Diabetic Peripheral Neuropathy
Administration
May be taken with or without food.
Adult Dose
Oral Moderate to severe acute pain Adult: Initially, 50 mg, 75 mg or 100 mg 4-6 hrly, depending on pain intensity. On day 1, a 2nd dose may be given... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment CrCl >30 mL/min : Dosage adjustment not required CrCl <30 mL/min: Not recommended
Contraindication
Significant resp depression (in unmonitored settings or absence of resuscitative equipment), acute or severe bronchial asthma or hypercapnia, known or s... View More
Mode of Action
Mu-opioid agonist; inhibits ascending pain pathways, thus altering response to pain; produces analgesia, respiratory depression, and sedation; also inhi... View More
Precaution
Tapentadol should be administered with caution to patients with conditions accompanied by hypoxia, hypercapnia, respiratory problems such as: asthma, ch... View More
Side Effect
>10% Nausea (30%),Dizziness (24%),Vomiting (18%),Somnolence (15%) 1-10% (selected) Constipation (8%),Pruritus (5%),Xerostomia (4%),Fatigue (3%),Hyp... View More
Interaction
Potential severe adverse effects w/ MAOIs. CNS-active drugs; other serotonergic agents (including triptans, SSRIs, other SNRIs, lithium, sibutramine, fe... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More