Chelova 500 is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the ... View More
Uses of Chelova 500
Side effects of Chelova 500
How to use Chelova 500
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Chelova 500 is to be taken... View More
How Chelova 500 works
Chelova 500 traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.
What if you forget to take Chelova 500?
If you miss a dose of Chelova 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
Chronic iron overload.
Should be taken on an empty stomach. Take on an empty stomach at least 30 min before meals preferably at the same time daily. Disperse tab completely by... View More
Transfusional Hemosiderosis Indicated for treatment of chronic iron overload caused by blood transfusion 20 mg/kg PO qDay; may increase by 5-10 mg inc... View More
Transfusional Hemosiderosis Indicated for treatment of chronic iron overload caused by blood transfusion <2 years: Safety and efficacy not established... View More
Renal Impairment Baseline renal impairment CrCl 40-60 mL/min: Reduce starting dose by 50% Serum Cr >2 xULN or CrCl <40 mL/min: Do not use
Mode of Action
Deferasirox is an orally active chelator that is selective for iron (as Fe3+ ion). It is a tridentate ligand that binds iron with high affinity in a 2:1... View More
Monitor renal function and CBC before starting treatment and regularly during treatment; may need to reduce dose or stop treatment if serum creatinine l... View More
>10% Serum creatinine increase (dose related; 7-38%),Abdominal pain (21-28%),Nausea (11-23%),Vomiting (10-21%),Diarrhea (12-20%),Proteinuria (19%),Pyre... View More
Pregnancy Category Note
Pregnancy There are no studies with use in pregnant women to inform drug-associated risks; administration of deferasirox to rats during pregnancy resul... View More
Not to be used with aluminium-containing antacids as it may chelate aluminium.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More