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Chlorphen250mg

Capsule
Nipa Pharmaceuticals Ltd.
Generic: Chloramphenicol
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
Consuming alcohol while taking Chlorphen may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (D... View More
PregnancyPregnancy
CONSULT YOUR DOCTOR
Chlorphen may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developi... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Chlorphen is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Chlorphen may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
KidneyKidney
SAFE IF PRESCRIBED
Chlorphen is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Chlorphen may not be needed i... View More
LiverLiver
CONSULT YOUR DOCTOR
There is limited information available on the use of Chlorphen in patients with liver disease. Please consult your doctor.
descriptionMedical Overview

Introduction

Chlorphen is an antibiotic that fights bacteria. It is used to treat certain types of serious infections caused by bacteria when other antibiotics canno... View More

Uses of Chlorphen

  • Bacterial infections

Side effects of Chlorphen

Common
  • Vomiting
  • Nausea
  • Diarrhea
  • Taste change

How to use Chlorphen

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Chlorphen is to be taken empty stomach.

How Chlorphen works

Chlorphen is an antibiotic which stops the growth of bacteria. It does so by preventing synthesis of essential proteins required by bacteria to carry ou... View More

quick tipsQuick Tips
  • Your doctor has prescribed Chlorphen to cure your infection and improve your symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder ... View More
  • Your doctor may get blood tests done to check your blood cells before starting treatment and regularly thereafter.
  • Do not use Chlorphen if you are pregnant, planning to conceive, or breastfeeding.
  • Inform your doctor if you have liver or kidney disease.
descriptionBrief Description

Indication

Tetracycline-resistant cholera, typhoid, brain abscesses, meningitis, Granuloma inguinale, Anthrax, Listeriosis, Gas gangrene, Whipple's disease, gastro... View More

Administration

Should be taken on an empty stomach. Take on an empty stomach 1 hr before or 2 hr after meals.

Adult Dose

Adult: PO Susceptible infections 50 mg/kg/day in 4 divided doses, may increase to 100 mg/kg/day in more severe infections. Hepatic impairment: Dose ... View More

Child Dose

PO Susceptible infections Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divid... View More

Renal Dose

Renal impairment: Dose reduction may be required.

Contraindication

History of hypersensitivity or toxic reaction to the drug; pregnancy, lactation; porphyria; parenteral admin for minor infections or as prophylaxis; pre... View More

Mode of Action

Chloramphenicol inhibits bacterial protein synthesis by binding to 50s subunit of the bacterial ribosome, thus preventing peptide bond formation by pept... View More

Precaution

Impaired renal or hepatic function; premature and full-term neonates. Monitor plasma concentrations to avoid toxicity. Lactation: enters breast milk;... View More

Side Effect

<1% Nightmares,Headache,Rash,Diarrhea,Stomatitis,Enterocolitis,Nausea,Vomiting,Bone marrow suppression,Aplastic anemia,Peripheral neuropathy,Optic neur... View More

Pregnancy Category Note

Pregnancy Category: C Lactation: enters breast milk; discontinue drug or do not nurse

Interaction

Decreased effects of iron and vitamin B12 in anaemic patients. Phenobarbitone and rifampin reduce efficacy of chloramphenicol. Impairs the action of ora... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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