Cisplathin Hexal1mg/2ml
Injection
Novartis (Bangladesh) Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Cisplathin Hexal. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Cisplathin Hexal is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescrib... View More |
| Breastfeeding | UNSAFE Cisplathin Hexal is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | UNSAFE Cisplathin Hexal may cause side effects which could affect your ability to drive.
Cisplathin Hexal may cause side effects such as feeling sleepy and/or ... View More |
| Kidney | CAUTION Cisplathin Hexal should be used with caution in patients with kidney disease. Dose adjustment of Cisplathin Hexal may be needed. Please consult your doc... View More |
| Liver | SAFE IF PRESCRIBED Cisplathin Hexal is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Cisplathin Hexal may no... View More |
Introduction
Cisplathin Hexal is used in the treatment of ovarian, cervical and testicular cancer. It shows its working by stopping or slowing down the growth of can... View More
Uses of Cisplathin Hexal
- Ovarian cancer
- Cervical cancer
- Testicular cancer
Side effects of Cisplathin Hexal
- Injection site reactions (pain, swelling, redness)
- Increased risk of infection
- Ear disorder
- Vomiting
- Nausea
- Decreased blood cells (red cells, white cells, and platelets)
- Renal impairment
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Kidney damage
- Hearing loss
- Ringing in ear
How to use Cisplathin Hexal
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Cisplathin Hexal works
Cisplathin Hexal is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and ... View More
What if you forget to take Cisplathin Hexal?
If you miss a dose of Cisplathin Hexal, please consult your doctor.
- Cisplathin Hexal is given as an injection under the supervision of a doctor.
Indication
Lymphomas, Sarcomas, Carcinomas, Small cell lung cancer, Ovarian cancer, Germ cell tumors, Metastatic Testicular Tumors, Metastatic Ovarian Tumors, Adva... View More
Administration
IV Preparation Further dilution stability is dependent on chloride ion concentration & should be mixed in solutions of NS (at least 0.3% NaCl) Further... View More
Adult Dose
Metastatic Testicular Tumors Usual dose in combination with other approved chemotherapeutic agents is 20 mg/m²/day IV for 5 days/cycle Pretreatment h... View More
Renal Dose
Renal Impairment CrCl 10-50 mL/min: Decrease dose 50% CrCl <10 mL/min: Contraindicated
Contraindication
Patients with severe renal or auditory disorder, known hypersensitivity, severe bone marrow suppression, peripheral neuropathy, pregnancy, lactation.
Mode of Action
Cisplatin modifies cell cycle by interfering with DNA structure and function. Effects are most prominent during the S phase but cells are killed at all ... View More
Precaution
Patients with renal or hepatic disorder, myelosuppression. Monitor renal, neurological and auditory function. Perform blood counts regularly. Maintain a... View More
Side Effect
>10% Nausea (76-100%),Vomiting (76-100%),Nephrotoxicity (28-36%),Ototoxicity, especially in children (31%),Myelosuppression (25-30%),Anaphylaxis (1-20%... View More
Pregnancy Category Note
Pregnancy Based on human data from published literature, cisplatin can cause fetal harm when administered to pregnant women; data demonstrates transpla... View More
Interaction
Synergistic with 5-fluorouracil and etoposide. Efficacy increased and toxicity reduced when combined with radioprotecting agent WR 2721. At doses ?100 m... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More