Brigacent 9090mg
Tablet
Incepta Pharmaceuticals Ltd.
Additional Offers
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Indication
Non-Small Cell Lung Cancer
Administration
Take with or without food
Adult Dose
Non-Small Cell Lung Cancer Indicated for anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients who have p... View More
Renal Dose
Renal impairment Mild or moderate (CrCl 30-89 mL/min): No dose adjustment required Severe (CrCl 15-29 mL/min): Reduce brigatinib dose by ~50% (eg, f... View More
Mode of Action
Tyrosine kinase inhibitor with in vitro activity at clinically achievable concentrations against multiple kinases, including ALK, ROS1, insulinlike grow... View More
Precaution
Risk of interstitial lung disease (ILD)/pneumonitis; HTN; bradycardia; visual disturbances (eg, blurred vision, diplopia, & reduced visual acuity); crea... View More
Side Effect
>10% Increased AST (38%) Hyperglycemia (38%) Increased ALT (34%) Nausea (33%) Fatigue (29%) Headache (28%) Increased CPK (27%) Increased amylase... View More
Pregnancy Category Note
Pregnancy Based on its mechanism of action and findings in animals, can cause fetal harm when administered to pregnant women Administration to pregn... View More
Interaction
Increased plasma conc & adverse reactions w/ strong CYP3A inhibitors [eg, certain antivirals (boceprevir, cobicistat, indinavir, lopinavir, nelfinavir, ... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More