Introduction
Clobex is an antibiotic used to treat various bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract, ... View More
Uses of Clobex
Side effects of Clobex
How to use Clobex
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clobex is to be taken empt... View More
How Clobex works
Clobex is an antibiotic. It kills bacteria by preventing them from forming their own protective covering (cell wall) which is needed for them to survive... View More
Indication
Staphylococcal infections resistant to benzylpenicillin
Administration
Should be taken on an empty stomach. Take on an empty stomach 1 hr before or 2 hr after meals. Reconstitution: IM: The contents of each vial should b... View More
Adult Dose
Oral Adult: 250-500 mg 4 times/day. Parenteral Adult: 1-2 g 6 hrly. For more severe infections (e.g. meningitis, endocarditis), 2 g 4 hrly.
Child Dose
Oral Child: 50-100 mg/kg in divided doses every 6 hr.
Contraindication
Hypersensitivity to cloxacillin and other penicillins.
Mode of Action
Cloxacillin inhibits bacterial cell wall synthesis by binding to 1 or more of the penicillin-binding proteins (PBPs) which in turn inhibit the final tra... View More
Precaution
Patient w/ allergies esp β-lactam allergy, asthma, history of seizure disorder. Renal impairment. Pregnancy and lactation. Monitoring Parameters Observe... View More
Side Effect
Hypotension, confusion, fever, lethargy, seizure, pruritus, rash, urticaria, abdominal pain, black or hairy tongue, diarrhoea, flatulence, nausea, oral ... View More
Interaction
May diminish the effect of BCG and typhoid vaccine. May increase risk of methotrexate toxicity. May diminish the therapeutic effect of Na picosulfate. M... View More
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More